Department of Oral and Maxillofacial Pathology, Dental Faculty, Tabriz University (Medical Sciences), Tabriz, Iran.
Med Oral Patol Oral Cir Bucal. 2011 Nov 1;16(7):e1014-6. doi: 10.4317/medoral.17158.
The aim of this study was to evaluate microleakage of white mineral trioxide aggregate (WMTA) after its exposure to a range of alkaline environments during hydration.
Seventy single-rooted teeth were divided into 4 experimental and 2 control groups. All the teeth were instrumented, and their apices were resected. Root-end cavities were filled with WMTA in the experimental groups. In the control groups, root-end cavities were not filled. Root-end fillings were exposed to alkaline environments with pH values of 7.4, 8.4, 9.4, or 10.4 for 3 days. Microleakage was evaluated by bovine serum albumin. Evaluations were carried out at 24-hour intervals for 80 days. Data were analyzed by one-way analysis of variance and a post hoc Tukey test at the 0.05 level of confidence.
The number of days (mean ± standard deviation) needed for color change at pH values of 7.4, 8.4, 9.4, and 10.4 were 78.53 ± 5.68, 80.00 ± 0.00, 68.93 ± 19.00, and 34.46 ± 12.73, respectively. The time needed for leakage to occur was significantly shorter in samples stored at a pH value of 10.4 (P<0.001).
Within the limits of this study, it can be concluded that pH values greater than 9.4 may jeopardize the sealing ability of WMTA during hydration.
本研究旨在评估在水化过程中暴露于一系列碱性环境下时，白色矿物三氧化物聚合体（WMTA）的微渗漏情况。
70 颗单根牙被分为 4 个实验组和 2 个对照组。所有牙齿均经过器械处理，并切除根尖。实验组的根尖腔用 WMTA 填充。对照组的根尖腔则未填充。将根尖填充物暴露于 pH 值分别为 7.4、8.4、9.4 和 10.4 的碱性环境中 3 天。采用牛血清白蛋白评估微渗漏。在 80 天内，每 24 小时评估一次。数据采用单因素方差分析和事后 Tukey 检验进行分析，置信水平为 0.05。
pH 值为 7.4、8.4、9.4 和 10.4 时，颜色变化所需的天数（平均值±标准差）分别为 78.53±5.68、80.00±0.00、68.93±19.00 和 34.46±12.73。在 pH 值为 10.4 的样本中，发生泄漏所需的时间明显更短（P<0.001）。
在本研究的范围内，可以得出结论，pH 值大于 9.4 可能会危及 WMTA 在水化过程中的密封能力。
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