焦虑及焦虑障碍的脑血流和代谢。
Cerebral blood flow and metabolism in anxiety and anxiety disorders.
机构信息
MD, FRCPsych, Professor of Psychiatry, Associate Professor of Radiology, Box 3972, Duke University Medical Centre, Durham, North Carolina 27710, U.S.A.
出版信息
Indian J Psychiatry. 1994 Jul;36(3):103-20.
Anxiety disorders are some of the commonest psychiatric disorders and anxiety commonly co-exists with other psychiatric conditions. Anxiety can also be a normal emotion. Thus, study of the neurobiological effects of anxiety is of considerable significance. In the normal brain, cerebral blood flow (CBF) and metabolism (CMR) serve as indices of brain function. CBF/CMR research is expected to provide new insight into alterations in brain function in anxiety disorders and other psychiatric disorders. Possible associations between stress I anxiety I panic and cerebral ischemia I stroke give additional significance to the effects of anxiety on CBF. With the advent of non-invasive techniques, study of CBF/CMR in anxiety disorders became easier. A large numbers of research reports are available on the effects of stress, anxiety and panic on CBF/CMR in normals and anxiety disorder patients. This article reviews the available human research on this topic.
焦虑障碍是最常见的精神障碍之一，焦虑症常与其他精神疾病并存。焦虑也可能是一种正常的情绪。因此，研究焦虑的神经生物学效应具有重要意义。在正常大脑中，脑血流 (CBF) 和代谢 (CMR) 是脑功能的指标。CBF/CMR 研究有望为焦虑症和其他精神障碍中脑功能的改变提供新的见解。应激、焦虑、惊恐与脑缺血、中风之间的可能关联，使焦虑对 CBF 的影响具有额外的意义。随着非侵入性技术的出现，对焦虑症患者 CBF/CMR 的研究变得更加容易。关于应激、焦虑和惊恐对正常人和焦虑症患者 CBF/CMR 的影响，已有大量研究报告。本文综述了这一主题的现有人类研究。
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