Department of Obstetrics and Gynaecology, McGill University Health Center, 687 Pine Ave. West, Montreal, QC H3A 1A1, Canada.
Department of Pathology, McGill University Health Center, 687 Pine Ave. West, Montreal, QC H3A 1A1, Canada.
Placenta. 2011 Sep;32(9):671-674. doi: 10.1016/j.placenta.2011.06.007. Epub 2011 Jul 13.
To evaluate pregnancy outcome and ultrasound diagnosis in patients with histologically-confirmed placental chorioangioma.
Placentas with histological diagnosis of chorioangioma were identified and medical charts were reviewed for findings of ultrasound examinations. Pregnancy outcomes were compared with all singleton deliveries without chorioangioma in the same time period.
Primary outcome was Neonatal Intensive Care Unit admission rate. Secondary outcome was ultrasound detection rate of chorioangioma.
Among 14,725 singleton deliveries, 23 placentas were diagnosed with chorioangioma (0.16%). The control group included all singleton deliveries without chorioangioma (n = 14702). Neonates in the study group were more likely to be admitted to the Neonatal Intensive Care Unit (OR = 4.45) and to have smaller birth weight (p = 0.006). Only 2 of 7 larger chorioangiomas (≥ 2 cm) with available ultrasound reports were identified by ultrasound (29% detection rate). All cases demonstrated normal fetal growth and wellbeing.
Chorioangiomas are not always identified by routine prenatal sonography. Even in the absence of ultrasonic abnormalities, neonatal morbidity, as measured by NICU admission rate, is increased.
评估组织学确诊的胎盘绒毛血管瘤患者的妊娠结局和超声诊断。
确定具有绒毛血管瘤组织学诊断的胎盘，并回顾超声检查的发现。将妊娠结局与同期内无绒毛血管瘤的所有单胎分娩进行比较。
主要结局是新生儿重症监护病房（NICU）入院率。次要结局是超声对绒毛血管瘤的检出率。
在 14725 例单胎分娩中，有 23 例胎盘被诊断为绒毛血管瘤（0.16%）。对照组包括所有无绒毛血管瘤的单胎分娩（n=14702）。研究组的新生儿更有可能被收入新生儿重症监护病房（OR=4.45），且出生体重更小（p=0.006）。在有超声报告的 7 个较大绒毛血管瘤（≥2cm）中，仅 2 个（29%的检出率）被超声识别。所有病例均显示胎儿生长和健康状况正常。
绒毛血管瘤并不总是通过常规产前超声检查识别。即使没有超声异常，NICU 入院率衡量的新生儿发病率也会增加。
