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26例经组织学证实的胎盘绒毛膜血管瘤患者的临床分析

Clinical analysis of 26 patients with histologically proven placental chorioangiomas.

作者信息

Wu Zaigui, Hu Wensheng

机构信息

Zhejiang University, School of Medicine, Women's Hospital, Department of Obstetrics and Gynecology, 1 Xueshi Road, Hangzhou 310006, Zhejiang, PR China.

Zhejiang University, School of Medicine, Women's Hospital, Department of Obstetrics and Gynecology, 1 Xueshi Road, Hangzhou 310006, Zhejiang, PR China.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2016 Apr;199:156-63. doi: 10.1016/j.ejogrb.2015.12.009. Epub 2015 Dec 30.

Abstract

OBJECTIVES

The purpose of this study was to evaluate the clinical characteristics, imaging features, pregnancy complications, prenatal management of patients with placenta chorioangioma.

METHODS

This was a retrospective study of 26 cases with histologically proven placenta chorioangima, in which the natural history, pregnancy complications, and clinical characteristics including ultrasonography were evaluated.

RESULTS

Twelve of the twenty-six cases had a wide range of maternal-fetal complications including polyhydramnios (7), fetal growth restriction (3), fetal distress (2), pre-eclampsia (3), fetal anemia-thrombocytopenia (2), congestive heart failure (1) and fetal abnormality (1).

CONCLUSIONS

Placenta chorioangioma was associated with series of pregnancy complications such as polyhytramnios, premature delivery, maternal pre-eclampsia, fetal growth restriction, fetal distress, even fetal anemia and cardiomegaly. With regular prenatal examination, necessary treatment, and timely delivery, the majority had a good pregnancy outcome.

摘要

目的

本研究旨在评估胎盘绒毛膜血管瘤患者的临床特征、影像学特征、妊娠并发症及产前管理情况。

方法

这是一项对26例经组织学证实为胎盘绒毛膜血管瘤病例的回顾性研究,评估其自然病史、妊娠并发症及包括超声检查在内的临床特征。

结果

26例病例中有12例出现了一系列母胎并发症,包括羊水过多(7例)、胎儿生长受限(3例)、胎儿窘迫(2例)、子痫前期(3例)、胎儿贫血 - 血小板减少(2例)、充血性心力衰竭(1例)及胎儿畸形(1例)。

结论

胎盘绒毛膜血管瘤与一系列妊娠并发症相关,如羊水过多、早产、母体子痫前期、胎儿生长受限、胎儿窘迫,甚至胎儿贫血和心脏肥大。通过定期产前检查、必要的治疗及适时分娩,大多数患者妊娠结局良好。

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