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胆管癌合并多发胆管微错构瘤。

Cholangiocarcinoma in association with multiple biliary microhamartomas.

作者信息

Burns C D, Kuhns J G, Wieman T J

机构信息

Department of Pathology and General Surgery, University of Louisville (Ky) School of Medicine.

出版信息

Arch Pathol Lab Med. 1990 Dec;114(12):1287-9.

PMID:2174673
Abstract

The rarity of cholangiocarcinoma occurring in von Meyenburg complexes is well appreciated. We describe the case of a 35-year-old man found to have cholangiocarcinoma in association with multiple biliary microhamartomas of the liver. Areas of ductal proliferation and atypia within the bile duct hamartomas suggest malignant transformation to cholangiocarcinoma.

摘要

胆管癌发生于梅耶堡复合体极为罕见,这一点已得到充分认识。我们报告一例35岁男性病例,该患者被发现患有胆管癌,同时伴有肝脏多发胆管微错构瘤。胆管错构瘤内的导管增生和异型性区域提示向胆管癌的恶性转化。

相似文献

1
Cholangiocarcinoma in association with multiple biliary microhamartomas.胆管癌合并多发胆管微错构瘤。
Arch Pathol Lab Med. 1990 Dec;114(12):1287-9.
2
[Cholangiocarcinoma arising from biliary micro-hamartomas in a man suffering from hemochromatosis].[一名患有血色素沉着症的男性患者中,源于胆管微小错构瘤的胆管癌]
Ann Pathol. 1997 Oct;17(5):346-9.
3
Hepatocellular carcinoma in association with bile duct hamartomas: report on 2 cases and review of the literature.肝细胞癌合并胆管错构瘤:2例报告及文献复习
Ann Diagn Pathol. 2008 Jun;12(3):208-11. doi: 10.1016/j.anndiagpath.2006.12.003. Epub 2007 Aug 10.
4
Hilar bile duct cancer associated with preoperatively undetectable von Meyenburg complex--report of a case.术前未检测到的先天性肝内胆管错构瘤合并肝门部胆管癌——病例报告
Hepatogastroenterology. 2004 Sep-Oct;51(59):1301-3.
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[Liver neoplasms in children].[儿童肝脏肿瘤]
Bol Med Hosp Infant Mex. 1981 Sep-Oct;38(5):723-40.
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[Cholangiocarcinoma developing in von Meyenburg complexes in haemochromatosis].[血色病中梅耶尔恩堡复合体发生的胆管癌]
Gastroenterol Clin Biol. 2002 Oct;26(10):922-4.
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Hepatocellular carcinoma arising in association with von-Meyenburg's complexes: an incidental finding or precursor lesions? A clinicopatholigic study of 4 cases.与 von-Meyenburg 复合体相关的肝细胞癌:偶然发现还是前驱病变?4 例临床病理研究。
Ann Diagn Pathol. 2010 Oct;14(5):317-20. doi: 10.1016/j.anndiagpath.2010.04.003. Epub 2010 Jun 25.
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Cholangiocarcinoma associated with multiple bile-duct hamartomas of the liver.与肝脏多发性胆管错构瘤相关的胆管癌
Dig Dis Sci. 1989 Jun;34(6):952-8. doi: 10.1007/BF01540285.
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Intrahepatic cholangiocarcinoma and portal hypertension developing in a patient with multicystic biliary microhamartomas.患有多囊性胆管微错构瘤的患者发生肝内胆管癌和门静脉高压症。
Malays J Pathol. 2018 Dec;40(3):331-335.
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Biliary hamartomas (von Meyenburg complexes) in liver needle biopsies.肝脏穿刺活检中的胆管错构瘤(冯·迈恩伯格复合体)
Acta Pathol Microbiol Scand A. 1978 Mar;86(2):93-9. doi: 10.1111/j.1699-0463.1978.tb02019.x.

引用本文的文献

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Intrahepatic cholangiocarcinoma developing from biliary hamartomas: A case report and literature review.起源于胆管错构瘤的肝内胆管癌:1例报告及文献复习
Int J Surg Case Rep. 2025 Aug;133:111524. doi: 10.1016/j.ijscr.2025.111524. Epub 2025 Jun 16.
2
Pediatric living donor liver transplantation for congenital hepatic fibrosis using a mother's graft with von Meyenburg complex: A case report.小儿先天性肝纤维化活体肝移植:使用母亲带有梅氏复合体的移植物的病例报告
World J Gastroenterol. 2016 Nov 28;22(44):9865-9870. doi: 10.3748/wjg.v22.i44.9865.
3
Lesions of biliary hamartoms can be diagnosed by ultrasonography, computed tomography and magnetic resonance imaging.
胆管错构瘤病变可通过超声检查、计算机断层扫描和磁共振成像来诊断。
Int J Clin Exp Med. 2014 Oct 15;7(10):3370-7. eCollection 2014.
4
Cholangiocarcinoma arising in von Meyenburg complexes.胆管错构瘤内发生的胆管癌。
Korean J Hepatol. 2011 Jun;17(2):161-4. doi: 10.3350/kjhep.2011.17.2.161.
5
Multiple biliary hamartomas: magnetic resonance features with histopathologic correlation.多发性胆管错构瘤:磁共振特征与组织病理学对照
Eur Radiol. 2008 Mar;18(3):493-9. doi: 10.1007/s00330-007-0790-z. Epub 2007 Oct 13.
6
Intrahepatic cholangiocarcinoma arising in autosomal dominant polycystic kidney disease.常染色体显性遗传性多囊肾病相关的肝内胆管癌
Virchows Arch. 2002 Jul;441(1):98-100. doi: 10.1007/s00428-002-0635-8. Epub 2002 Mar 26.
7
Coexisting extraadrenal pheochromocytoma and von Meyenberg complexes: report of a case.肾上腺外嗜铬细胞瘤与肝内胆管错构瘤并存:一例报告
Surg Today. 1999;29(1):80-2. doi: 10.1007/BF02482976.
8
Cholangiocarcinoma arising in bile duct adenoma with focal area of bile duct hamartoma.胆管腺瘤合并局灶性胆管错构瘤时发生的胆管癌。
Virchows Arch. 1995;426(2):209-13. doi: 10.1007/BF00192644.