Rehal Balvinder, Golshanara Neilu, Maguina Pirko
Shriners Hospital for Children, Northern California, Sacramento, CA, USA.
J Burn Care Res. 2011 Jul-Aug;32(4):475-80. doi: 10.1097/BCR.0b013e3182223c58.
Giant congenital melanocytic nevi (GCMN) are rare lesions that are present in 1 in every 20,000 new births. A 10-year review of all patients treated at a pediatric burn center was performed with the goal of identifying the characteristics of patients with GCMN and the outcomes of the treatment provided in a burn center. Thirty-six patients met the definition of GCMN; 64% were female and 36% were male. The most common ethnicity was white (47%), followed by Latino (19%). Most patients were between the ages of 1 and 10 years at the time of their first procedure (64%), and the mean age of patients at the time of their first procedure was 7 years. Eighty-nine percent had only one lesion. The most common location of lesions was the face (64%), followed by the scalp (17%) and back (17%). Seventy-four percent of the samples sent to pathology were congenital compound melanocytic nevi, and 20% were congenital intradermal melanocytic nevi. None of the lesions contained malignant changes at the time of the pathological examination. The various treatment modalities provided in the burn unit are reviewed. The authors conclude that the burn unit is an ideal setting for the treatment of GCMN.
巨大先天性黑素细胞痣（GCMN）是罕见的病变，每20000例新生儿中就有1例出现。对一家儿科烧伤中心治疗的所有患者进行了为期10年的回顾，目的是确定GCMN患者的特征以及烧伤中心提供的治疗结果。36例患者符合GCMN的定义；64%为女性，36%为男性。最常见的种族是白人（47%），其次是拉丁裔（19%）。大多数患者首次手术时年龄在1至10岁之间（64%），首次手术时患者的平均年龄为7岁。89%的患者只有一处病变。病变最常见的部位是面部（64%），其次是头皮（17%）和背部（17%）。送去做病理检查的样本中，74%是先天性复合黑素细胞痣，20%是先天性皮内黑素细胞痣。病理检查时所有病变均无恶性变化。本文回顾了烧伤科提供的各种治疗方式。作者得出结论，烧伤科是治疗GCMN的理想场所。
