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静脉内激光治疗:使用1500纳米和980纳米二极管激光之间存在临床差异吗?一项多中心随机临床试验。

Endovenous laser treatment: is there a clinical difference between using a 1500 nm and a 980 nm diode laser? A multicenter randomised clinical trial.

作者信息

Vuylsteke M, De Bo T H, Dompe G, Di Crisci D, Abbad C, Mordon S

机构信息

Department of Vascular Surgery, Sint-Andriesziekenhuis, Tielt, Belgium.

出版信息

Int Angiol. 2011 Aug;30(4):327-34.

PMID:21747351
Abstract

AIM

We compared the use of two different laser wavelengths in the treatment of great saphenous vein (GSV) reflux: the 1500 nm versus the 980 nm diode laser. We studied the occlusion rates and noted possible side-effects.

METHODS

In three centers 180 great saphenous veins were treated with endovenous laser ablation (EVLA). By random selection half of the patients were treated with a 980 nm laser and half with a 1500 nm laser. A Duplex scan was scheduled at one month and six months postoperatively. Ecchymosis was measured at one week using a calculated scale. In addition the need for analgesics, the induration around the treated vein and patient satisfaction rate were noted. At two weeks postoperatively a quality of life score (CIVIQ2) was obtained.

RESULTS

The complete occlusion rates at six months were not statistical significant different between both groups (95.5% for 980 nm and 93.1% for 1500 nm). Most of the non-occluded veins had a filiform internal lumen and did not show reflux. There was no significant difference in the postoperative appearance of ecchymosis (P=0.09). Patients treated with a 1500 laser had less induration around the treated vein (P=0.002), less need to take analgetics (1.8 days versus 2.9 days) and had a better postoperative quality of life (P=0.018). The patient satisfaction rate did not differ in the two groups.

CONCLUSION

Using a 1500 nm diode laser in the treatment of an incompetent GSV, compared to the use of a 980 nm laser, results in similar occlusion rates at six months, but somewhat less side-effects.

摘要

目的

我们比较了两种不同激光波长在治疗大隐静脉(GSV)反流中的应用:1500纳米与980纳米二极管激光。我们研究了闭塞率并记录了可能的副作用。

方法

在三个中心,180条大隐静脉接受了腔内激光消融术(EVLA)治疗。通过随机选择,一半患者接受980纳米激光治疗,另一半接受1500纳米激光治疗。术后1个月和6个月安排进行双功超声扫描。术后1周使用计算量表测量瘀斑情况。此外,记录了镇痛药物的使用需求、治疗静脉周围的硬结情况以及患者满意度。术后2周获得生活质量评分(CIVIQ2)。

结果

两组在6个月时的完全闭塞率无统计学显著差异(980纳米组为95.5%,1500纳米组为93.1%)。大多数未闭塞的静脉有丝状内腔且无反流。瘀斑的术后表现无显著差异(P = 0.09)。接受1500纳米激光治疗的患者治疗静脉周围的硬结较少(P = 0.002),镇痛药物使用需求较少(1.8天对2.9天),术后生活质量更好(P = 0.018)。两组患者的满意度无差异。

结论

与使用980纳米激光相比,使用1500纳米二极管激光治疗功能不全的大隐静脉,6个月时闭塞率相似,但副作用略少。

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