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用于多参数生化分析的集成光学传感器平台。

Integrated optical sensor platform for multiparameter bio-chemical analysis.

作者信息

Lützow Peter, Pergande Daniel, Heidrich Helmut

机构信息

Fraunhofer Institute for Telecommunications, Heinrich Hertz Institute, Berlin, Germany.

出版信息

Opt Express. 2011 Jul 4;19(14):13277-84. doi: 10.1364/OE.19.013277.

Abstract

There is growing demand for robust, reliable, low cost, and easy to use sensor systems that feature multiparameter analysis in many application areas ranging from safety and security to point of care and medical diagnostics. Here, we highlight the theory and show first experimental results on a novel approach targeting the realization of massively multiplexed sensor arrays. The presented sensor platform is based on arrays of frequency-modulated integrated optical microring resonators (MRR) fed by a single bus waveguide combined with lock-in detection to filter out in a reliable and simple manner their individual response to external stimuli. The working principle is exemplified on an array of four thermo-optically modulated MRR. It is shown that with this technique tracking of individual resonances is possible even in case of strong spectral overlap.

摘要

在从安全保障到即时护理和医疗诊断等众多应用领域,对具备多参数分析功能、强大、可靠、低成本且易于使用的传感器系统的需求日益增长。在此,我们重点介绍一种针对实现大规模复用传感器阵列的新方法的理论,并展示其初步实验结果。所提出的传感器平台基于由单个总线波导馈送的调频集成光学微环谐振器(MRR)阵列,并结合锁相检测,以可靠且简单的方式滤除它们对外部刺激的各自响应。以一个由四个热光调制MRR组成的阵列为例说明了其工作原理。结果表明,即使在光谱严重重叠的情况下,使用该技术也能够跟踪各个谐振。

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