Department of Paediatric Cardiology, Evelina Children's Hospital, Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom.
Catheter Cardiovasc Interv. 2011 Sep 1;78(3):405-12. doi: 10.1002/ccd.23023. Epub 2011 Jul 11.
To evaluate the mid and long-term prognosis after stenting of native or recurrent CoA, we studied the cardiovascular parameters in the follow-up period up to 13 years.
Between 1993 and 2006, 68 patients underwent stent implantation for aortic coarctation (average age 25.5 years, range 5.7-65 years, average weight 65.5 kg, range 32-122 kg). Forty-six (68%) patients were aged >17 years. Stenting was performed for native coarctation in 41 and for recurrent coarctation in 27 patients, in 23 (34%) patients with a covered stent. Redilation was carried out in 26 (38%) patients. The invasive systolic gradient decreased from mean (±SD) 25 (±15) mm Hg to 5 (±5) mm Hg (P < 0.0005). The descending aorta pressure increased from 80 (±15) mm Hg to 101 (±18) mm Hg. The systolic right arm blood pressure decreased from a mean of 153 (±24) mm Hg to 129 (±18) mm Hg (P < 0.0005). Complications like small dissections were rare. Follow-up (6 days to 13 years, mean 41 months) was available in 66 patients, in 23 after reintervention at a mean of 71 months, range of 8 months to 10.3 years. Fifty-one percent remained clinically hypertensive.
Stenting of aortic coarctation gives good medium-term results. Frequent reintervention relate to deliberately under-dilating stents during the initial procedure. The reintervention rate has reduced since the introduction of covered stents.
为了评估支架置入治疗先天性或复发性主动脉缩窄的中远期预后,我们对随访期内长达 13 年的心血管参数进行了研究。
1993 年至 2006 年间,68 例主动脉缩窄患者接受了支架植入术(平均年龄 25.5 岁,范围 5.7-65 岁,平均体重 65.5kg,范围 32-122kg)。46 例(68%)患者年龄>17 岁。支架置入治疗先天性主动脉缩窄 41 例,复发性主动脉缩窄 27 例,其中 23 例(34%)患者采用了覆膜支架。26 例(38%)患者进行了再扩张。有创收缩期梯度从平均(±SD)25(±15)mmHg 降至 5(±5)mmHg(P<0.0005)。降主动脉血压从 80(±15)mmHg 升至 101(±18)mmHg。收缩期右臂血压从平均 153(±24)mmHg 降至 129(±18)mmHg(P<0.0005)。小夹层等并发症罕见。66 例患者获得随访(6 天至 13 年,平均 41 个月),23 例患者在平均 71 个月(8 个月至 10.3 年)时再次介入。51%的患者仍有临床高血压。
主动脉缩窄支架置入术可获得良好的中期结果。频繁的再次介入与初始手术中支架故意过度扩张有关。自覆膜支架引入以来,再次介入的发生率有所降低。