Department of Forensic Science and Drug Monitoring, Franklin-Wilkins Building, King's College London SE1 9 NH, UK.
Drug Test Anal. 2011 Jul-Aug;3(7-8):479-82. doi: 10.1002/dta.318. Epub 2011 Jul 11.
Due to its closed ring system, 2-aminoindane is a conformationally rigid analogue of amphetamine. Internet websites offering synthetic compounds as 'research chemicals' have recently been advertising 5,6-methylenedioxy-2-aminoindane (MDAI), 5, 6-methylenedioxy-N-methyl-2-aminoindane (MDMAI), 5-iodo-2-aminoindane (5-IAI), and 5-methoxy-6-methyl-2-aminoindane (MMAI). The chemistry, pharmacology, and toxicological aspects of this new class of psychoactive substances are reviewed, as these could become the next wave of 'legal highs'.
由于其闭环系统，2-氨基茚满是安非他命的构象刚性类似物。提供合成化合物作为“研究用化学品”的互联网网站最近一直在宣传 5,6-亚甲二氧基-2-氨基茚满（MDAI）、5,6-亚甲二氧基-N-甲基-2-氨基茚满（MDMAI）、5-碘-2-氨基茚满（5-IAI）和 5-甲氧基-6-甲基-2-氨基茚满（MMAI）。本文综述了这一类新的精神活性物质的化学、药理学和毒理学方面，因为它们可能成为下一波“合法兴奋剂”。
