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儿童 1 型糖尿病患者心肺适能降低。

Lower cardiorespiratory fitness in children with Type 1 diabetes.

机构信息

School of Paediatrics and Child Health, The University of Western Australia, Crawley, WA, Australia.

出版信息

Diabet Med. 2011 Aug;28(8):1005-7. doi: 10.1111/j.1464-5491.2011.03271.x.

DOI:10.1111/j.1464-5491.2011.03271.x
PMID:21749445
Abstract

AIMS

The present study aimed to compare cardiorespiratory fitness levels in children with and without Type 1 diabetes. In addition, the relationship between cardiorespiratory fitness and a range of physical and clinical factors was investigated.

METHODS

Eighty-eight children with Type 1 diabetes aged 5-14 years completed a submaximal step test of cardiorespiratory fitness. Sixty-two of these children were successfully matched to control subjects without diabetes based on age, sex and anthropometrics for comparison. In addition, the relationship between cardiorespiratory fitness and a range of physical and clinical variables was assessed in the children with diabetes.

RESULTS

The heart rate response to exercise was higher in children with Type 1 diabetes, indicating reduced cardiorespiratory fitness levels compared with control subjects. Both gender and glycaemic control (HbA(1c) ) were significantly associated with cardiorespiratory fitness, with female sex and poorer glycaemic control associated with reduced fitness.

CONCLUSIONS

Future research should investigate whether the reduced fitness in children with Type 1 diabetes is attributable to lower physical activity levels, or physiological changes resulting from the diabetes pathology itself.

摘要

目的

本研究旨在比较患有 1 型糖尿病和不患有 1 型糖尿病儿童的心肺适能水平。此外,还研究了心肺适能与一系列身体和临床因素之间的关系。

方法

88 名年龄在 5-14 岁的 1 型糖尿病儿童完成了心肺适能的亚最大踏步测试。其中 62 名儿童根据年龄、性别和人体测量学成功与无糖尿病的对照组相匹配进行比较。此外,还评估了糖尿病儿童的心肺适能与一系列身体和临床变量之间的关系。

结果

1 型糖尿病儿童的运动时心率反应更高,表明与对照组相比,心肺适能水平降低。性别和血糖控制(HbA1c)与心肺适能显著相关,女性和血糖控制较差与较低的体能相关。

结论

未来的研究应该调查 1 型糖尿病儿童的这种体能下降是否归因于较低的身体活动水平,还是糖尿病病理本身导致的生理变化。

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