Calella Patrizia, Vitucci Daniela, Zanfardino Angela, Cozzolino Francesca, Terracciano Alessia, Zanfardino Francesco, Rollato Serena, Piscopo Alessia, Gallè Francesca, Mancini Annamaria, Di Onofrio Valeria, Iafusco Dario, Valerio Giuliana, Buono Pasqualina, Liguori Giorgio
Department of Movement Sciences and Wellbeing, University of Naples "Parthenope", Naples, Italy.
CEINGE Biotecnologie Avanzate "Franco Salvatore", Naples, Italy.
Heliyon. 2023 Jan 21;9(1):e13109. doi: 10.1016/j.heliyon.2023.e13109. eCollection 2023 Jan.
The association between Type 1 Diabetes Mellitus (T1DM) and obesity (Ob) is no longer unexpected due to unhealthy lifestyle mostly in adolescents. We compared clinical-biochemical characteristics, adherence to the Mediterranean Diet (MD), lifestyle habits and physical fitness across different weight categories of T1DM adolescents from Campania Region. As second aim, we assessed the relationship among lifestyle and physical fitness in these patients.
74 adolescents (35M; 39F; 13-18 y), with T1DM diagnosed at least 6 mo before the study, were enrolled at the Regional Center for Pediatric Diabetology of Vanvitelli University of Naples. Height, weight, Body Mass Index (BMI), BMI z-score, and Clinical Biochemical health-related parameters were determined. MD adherence, physical activity (PA) amount and sedentary habits were assessed by questionnaires. Handgrip strength, 2-Min Step test (2-MST) cardiorespiratory endurance and Timed up and go test (TUG) for agility and balance were used for physical fitness evaluation.
Our sample included 22 normal weight (NW), 37 overweight (OW) and 15 with Obese (Ob) adolescents. Across the three groups, adolescents showed similar Clinical-Biochemical parameters, MD adherence, PA amount, mostly walking (9.3 h/w), daily video exposure (8.5 h/d) and similar handgrip or 2-MST performance. Better performance was observed in NW compared to OW or Ob for TUG (7 8 9 s; p < 0.05). A positive correlation was found between TUG test and BMI, while no correlation was found between HbA1c (glycated haemoglobin) and BMI z score or 2-MST.
T1DM adolescents did not meet the recommendations for active lifestyle, despite a medium/good adherence to MD, in particular in NW and OW youths. Sedentary habits correlated with a poor HbA1c. Further, reduced agility and balance were observed in adolescents with obesity compared to NW participants.Future research should be aimed to examine wider samples and to design health promotion interventions for T1DM adolescents.
由于青少年大多生活方式不健康，1型糖尿病（T1DM）与肥胖（Ob）之间的关联已不再出人意料。我们比较了坎帕尼亚地区不同体重类别的T1DM青少年的临床生化特征、对地中海饮食（MD）的依从性、生活习惯和身体素质。作为第二个目标，我们评估了这些患者生活方式与身体素质之间的关系。
74名青少年（35名男性；39名女性；13 - 18岁），在研究前至少6个月被诊断为T1DM，在那不勒斯范维泰利大学儿科糖尿病区域中心登记入组。测定身高、体重、体重指数（BMI）、BMI z评分以及临床生化健康相关参数。通过问卷评估MD依从性、身体活动（PA）量和久坐习惯。使用握力、2分钟台阶试验（2 - MST）评估心肺耐力以及计时起立行走试验（TUG）评估敏捷性和平衡能力来进行身体素质评估。
我们的样本包括22名正常体重（NW）、37名超重（OW）和15名肥胖（Ob）青少年。在三组中，青少年表现出相似的临床生化参数、MD依从性、PA量，主要是步行（9.3小时/周）、每日视频观看时间（8.5小时/天）以及相似的握力或2 - MST表现。与OW或Ob相比，NW在TUG测试中表现更好（7 8 9秒；p < 0.05）。TUG测试与BMI之间存在正相关，而糖化血红蛋白（HbA1c）与BMI z评分或2 - MST之间未发现相关性。
T1DM青少年尽管对MD有中等/良好的依从性，但并未达到积极生活方式的建议，尤其是在NW和OW青少年中。久坐习惯与较差的HbA1c相关。此外，与NW参与者相比，肥胖青少年的敏捷性和平衡能力下降。未来的研究应旨在研究更广泛的样本，并为T1DM青少年设计健康促进干预措施。
