Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Kajii-cho, Kamigyo-ku, Japan.
Am J Reprod Immunol. 2011 Nov;66(5):410-5. doi: 10.1111/j.1600-0897.2011.01051.x. Epub 2011 Jul 12.
Chronic endometritis is an elusive entity that is often asymptomatic and undetectable by conventional endometrial biopsy and histological examination. Using immunohistochemistry for full-thickness endometrium, we sought for its clinicopathological features.
Two hundred and thirty-four archival endometrial specimens obtained by hysterectomy were immunostained for the plasmacyte marker syndecan-1 to identify chronic endometritis. Endometrial morphology was dated by the standard criteria. The immunoreactive cells were enumerated in 10 non-overlapping endometrial stromal areas. The clinical parameters were obtained from the medical charts.
Chronic endometritis was identified in 11.1% of the samples examined. Its occurrence was similar between the proliferative phase and secretory phase. A total of 23.1% of the cases were asymptomatic. Stromal plasmacyte infiltration and morphological delay were more prominent in symptomatic chronic endometritis than in asymptomatic counterpart.
Chronic endometritis is a common gynecological pathological condition and more often asymptomatic than ever expected. There was no menstrual cycle-dependent fluctuation in its occurrence.
慢性子宫内膜炎是一种难以捉摸的疾病，通常无症状，且通过常规子宫内膜活检和组织学检查无法检测到。我们使用全层子宫内膜的免疫组织化学方法，研究其临床病理特征。
对 234 例因子宫切除术获得的存档子宫内膜标本进行浆细胞标志物 syndecan-1 的免疫染色，以识别慢性子宫内膜炎。根据标准标准对子宫内膜形态进行分期。在 10 个非重叠的子宫内膜基质区域中对免疫反应细胞进行计数。临床参数从病历中获得。
在所检查的样本中，11.1%被确定为慢性子宫内膜炎。其发生在增生期和分泌期相似。无症状病例占 23.1%。与无症状组相比，有症状的慢性子宫内膜炎中基质浆细胞浸润和形态延迟更为明显。
慢性子宫内膜炎是一种常见的妇科病理状况，比预期更常无症状。其发生没有月经周期依赖性波动。
