Clinical Neurosciences Department, Neurology Service Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.
Eur J Neurol. 2011 Aug;18(8):1094-7. doi: 10.1111/j.1468-1331.2010.03264.x. Epub 2010 Nov 30.
Socioeconomic status is thought to have a significant influence on stroke incidence, risk factors and outcome. Its influence on acute stroke severity, stroke mechanisms, and acute recanalisation treatment is less known.
Over a 4-year period, all ischaemic stroke patients admitted within 24h were entered prospectively in a stroke registry. Data included insurance status, demographics, risk factors, time to hospital arrival, initial stroke severity (NIHSS), etiology, use of acute treatments, short-term outcome (modified Rankin Scale, mRS). Private insured patients (PI) were compared with basic insured patients (BI).
Of 1062 consecutive acute ischaemic stroke patients, 203 had PI and 859 had BI. They were 585 men and 477 women. Both populations were similar in age, cardiovascular risk factors and preventive medications. The onset to admission time, thrombolysis rate, and stroke etiology according to TOAST classification were not different between PI and BI. Mean NIHSS at admission was significantly higher for BI. Good outcome (mRS≤2) at 7days and 3months was more frequent in PI than in BI.
We found better outcome and lesser stroke severity on admission in patients with higher socioeconomic status in an acute stroke population. The reason for milder strokes in patients with better socioeconomic status in a universal health care system needs to be explained.
社会经济地位被认为对卒中发病率、危险因素和结局有重大影响。但其对急性卒中严重程度、卒中机制和急性再通治疗的影响知之甚少。
在 4 年期间,所有在 24 小时内入院的缺血性卒中患者前瞻性地纳入卒中登记。数据包括保险状况、人口统计学、危险因素、到达医院的时间、初始卒中严重程度(NIHSS)、病因、急性治疗的使用、短期结局(改良 Rankin 量表,mRS)。私人保险患者(PI)与基本保险患者(BI)进行比较。
在 1062 例连续急性缺血性卒中患者中,203 例为 PI,859 例为 BI。他们中有 585 名男性和 477 名女性。PI 和 BI 在年龄、心血管危险因素和预防药物方面相似。PI 和 BI 之间的发病到入院时间、溶栓率和根据 TOAST 分类的卒中病因无差异。BI 的入院时 NIHSS 平均值明显较高。PI 的 7 天和 3 个月时良好结局(mRS≤2)更为常见。
在急性卒中人群中,我们发现社会经济地位较高的患者结局更好,入院时卒中严重程度较低。在全民健康保障体系中,需要解释为何社会经济地位较好的患者卒中程度较轻。