Deaconess Clinic, 4055 Gateway Boulevard, Newburgh, IN 47630, USA.
Heart Fail Clin. 2011 Jul;7(3):427-35. doi: 10.1016/j.hfc.2011.04.004.
Chemotherapy-induced cardiotoxicity (CIC) is a major complication found with some life-saving medications used to treat breast and other cancers. Cardiotoxicity may present immediately during treatment or years later. These patients need education, screening, preventive measures, prompt interventions, and proper follow-up. This article focuses on CIC in patients who have breast cancer, but the process of evaluation and treatment design applies to all types of cancer and organ toxicities. Comprehensive pretreatment history, examination, and testing are needed for proper diagnosis and staging. CIC and other toxicities need to be considered in drug selection, treatment sequencing, testing, and appropriate follow-up.
化疗引起的心脏毒性(CIC)是一些用于治疗乳腺癌和其他癌症的救命药物的主要并发症。心脏毒性可能在治疗期间立即出现,也可能在数年后出现。这些患者需要接受教育、筛查、预防措施、及时干预和适当的随访。本文重点介绍患有乳腺癌的患者的 CIC,但评估和治疗设计的过程适用于所有类型的癌症和器官毒性。适当的诊断和分期需要全面的预处理病史、检查和测试。在药物选择、治疗顺序、测试和适当的随访中需要考虑 CIC 和其他毒性。