Rassow J, Baumhoer W, Olthoff K, Bamberg M
Institut für Medizinische Strahlenphysik, Universitätsklinikum Essen, F.R.G.
Radiother Oncol. 1990 Oct;19(2):179-85. doi: 10.1016/0167-8140(90)90131-f.
If astrocytomas of grade III and IV and pencil gliomas of the spinal cord would be good indications for neutron therapy, high accuracy and homogeneity of the target absorbed dose and the planned spatial dose distribution would be pre-conditions for acceptable low complication rates. Therefore, results of treatment planning calculations have been compared with in vivo measurements and found to be in good agreement. Special care is necessary if the percentage of the gamma-ray component is spatially varying and additionally for fixation of the patient and combination of radiation fields in the case of pencil gliomas. Examples are given how to avoid overdosage and to hold the inhomogeneity even at the borderline of adjacent fields within 10%.
如果III级和IV级星形细胞瘤以及脊髓的铅笔形胶质瘤是中子治疗的良好适应症，那么靶区吸收剂量的高精度和均匀性以及计划的空间剂量分布将是可接受的低并发症发生率的前提条件。因此，已将治疗计划计算结果与体内测量结果进行了比较，发现两者吻合良好。如果伽马射线成分的百分比在空间上变化，并且在铅笔形胶质瘤的情况下，对于患者的固定和辐射野的组合，则需要特别小心。给出了如何避免过量照射以及如何将相邻野边界处的不均匀性保持在10%以内的示例。
