Division of Breast and Soft Tissue Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
J Surg Oncol. 2012 Feb;105(2):212-20. doi: 10.1002/jso.22020. Epub 2011 Jul 12.
The incidence of ductal carcinoma in situ (DCIS) has increased because of increasing use of sensitive imaging modalities. MRI is commonly used for the detection of breast cancer but has not yet been validated in randomized trials. There have not been randomized trials addressing optimal margins of excision or axillary sampling. Whole breast radiation after lumpectomy decreases the risk of recurrence but may be omitted in selected patients. Adjuvant Tamoxifen reduces the risk of recurrence but has no impact on overall survival rates.
由于敏感成像方式的广泛应用，导管原位癌（DCIS）的发病率有所增加。磁共振成像（MRI）常用于乳腺癌的检测，但尚未在随机试验中得到验证。目前尚无针对最佳切除边缘或腋窝取样的随机试验。保乳手术后行全乳腺放疗可降低复发风险，但在某些特定患者中可以省略。辅助他莫昔芬可降低复发风险，但对总生存率无影响。
