Iovchuk N M
Zh Nevropatol Psikhiatr Im S S Korsakova. 1990;90(8):52-6.
Based on a ++clinico-statistical analysis of patients (n-159) with cyclothymia and schizophrenia with predominant affective symptomatology who fell ill in childhood and were followed up for 5 to 18 years the main tendencies of the disease course and different patterns of the personality dynamics were discovered, correlating with a number of the premorbid characteristics and the structure of the first attack. The mathematic treatment using the Boolean model enabled one to obtain a prognostic model which may form the basis for the expert system to objectively evaluate, specify and accelerate the process of individual forecasting in the endogenous affective syndromes in childhood. The author provides evidence for relativity of the alternative importance of the clinical signs whose genuine prognostic weight only becomes known in diverse combinations with the other signs.
基于对159例儿童期发病并随访5至18年的环性心境障碍和以情感症状为主的精神分裂症患者的临床统计学分析,发现了疾病进程的主要趋势和人格动力学的不同模式,这些与许多病前特征和首次发作的结构相关。使用布尔模型进行数学处理,能够获得一个预后模型,该模型可为专家系统提供基础,以便客观评估、明确并加速儿童期内源性情感综合征的个体预测过程。作者提供了临床体征替代重要性的相对性证据,其真正的预后权重只有在与其他体征的不同组合中才会知晓。