Institute of Pathology, Locarno, Switzerland.
Cancer Cytopathol. 2012 Apr 25;120(2):73-86. doi: 10.1002/cncy.20178. Epub 2011 Jul 12.
Thyroid fine-needle aspiration has developed into a key test in the evaluation of thyroid nodules. Although the interpretation of thyroid aspirates containing mild abnormalities is problematic, the introduction of the atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) category in The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) has helped to delineate such cases in a systematic and clinically meaningful manner. Herein the authors review the cytomorphologic features associated with the AUS/FLUS interpretation and summarize the results of studies conducted since the implementation of TBSRTC.
甲状腺细针抽吸术已发展成为评估甲状腺结节的关键检测手段。虽然含有轻度异常的甲状腺抽吸物的解读存在问题，但在《甲状腺细胞病理学报告的 Bethesda 系统》（TBSRTC）中引入意义不明确的非典型性/意义不明确的滤泡性病变（AUS/FLUS）类别有助于以系统和具有临床意义的方式描绘此类病例。本文作者回顾了与 AUS/FLUS 解读相关的细胞形态学特征，并总结了自 TBSRTC 实施以来开展的研究结果。
