Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
Am J Clin Pathol. 2011 Dec;136(6):896-902. doi: 10.1309/AJCPIX52MBOKTICP.
The "Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance (AUS/FLUS)" category in the Bethesda System for Reporting Thyroid Cytology is heterogeneous and includes both specimens with borderline cellularity/compromised quality and those with genuine atypia. We have used a reporting scheme that is similar to the Bethesda System but does not include an AUS/FLUS category. We retrospectively reviewed all reports on thyroid FNA and thyroidectomy specimens submitted to the Beth Israel Deaconess Medical Center from January 2006 to December 2008. The positive predictive values for various categories and subcategories in this scheme demonstrate that the AUS/FLUS category can be eliminated to provide information for the most appropriate management of patients with thyroid nodules.
在甲状腺细胞病理学报告的 Bethesda 系统中，“意义不明确的非典型性/滤泡性病变意义不明确（AUS/FLUS）”这一类别具有异质性，其中既包括细胞界限模糊/质量欠佳的标本，也包括真正意义上的不典型性标本。我们采用了一种类似于 Bethesda 系统但不包括 AUS/FLUS 类别的报告方案。我们对 2006 年 1 月至 2008 年 12 月间提交给 Beth Israel Deaconess Medical Center 的所有甲状腺细针穿刺抽吸（FNA）和甲状腺切除术标本的报告进行了回顾性研究。该方案中各分类和亚分类的阳性预测值表明，可以排除 AUS/FLUS 类别，为甲状腺结节患者的最佳管理提供信息。
