Lewandowicz-Uszyńska Aleksandra, Szaflarska Anna, Pietrucha Barbara, Tarnowska Iwona
III Katedra Pediatrii Klinika Immunologii i Reumatologii Wieku Rozwojowego AM we Wrocławiu.
Pol Merkur Lekarski. 2011 Jun;30(180):452-7.
Primary immunodeficiency diseases (PIDs) are presenting the most common in childhood. PID are genetically determined disorders of the immune system resulting in greatly enhanced susceptibility to infectious disease. Therapy in these group of patients preventing infectious diseases is immunoglobulin (Ig) replacement therapy. Nowadays the quality of life is very important issue which doctors should consider treating their patients. The subcutaneous immunoglobulins appears to be the best solution for them. Treating patients with subcutaneous Ig require good educational programme not only for patients but also for doctors and nurses. We would like to provide practical guidelines for identifying patients who should be referred for assessment of possible immunodeficiency and give some practical instructions how to start and follow-up subcutaneous therapy in all centers of immunology in Poland who are engaged in this kind of treatment.
原发性免疫缺陷病(PIDs)在儿童期最为常见。PID是由基因决定的免疫系统疾病,会导致对传染病的易感性大大增强。在这类患者中预防传染病的治疗方法是免疫球蛋白(Ig)替代疗法。如今,生活质量是医生在治疗患者时应考虑的非常重要的问题。皮下注射免疫球蛋白似乎是对他们最好的解决方案。用皮下Ig治疗患者不仅需要为患者,也需要为医生和护士提供良好的教育方案。我们希望提供实用指南,以确定应转诊以评估可能存在免疫缺陷的患者,并给出一些实用指导,说明在波兰所有从事此类治疗的免疫学中心如何开始和随访皮下治疗。