Department of Anaesthesiology and Intensive Care, Stavanger University Hospital, Norway.
Resuscitation. 2011 Dec;82(12):1508-13. doi: 10.1016/j.resuscitation.2011.06.016. Epub 2011 Jun 24.
Out-of-hospital cardiac arrest (OHCA) is a major cause of death in the western world. We wanted to study changes in survival over time and factors linked to this in a region which have already reported high survival rates.
We used a prospectively collected Utstein template database to identify all resuscitation attempts in adult patients with OHCA of presumed cardiac origin. We included 846 resuscitation attempts and compared survival to discharge with good outcome in two time periods (2001-2005 vs. 2006-2008).
We found no significant differences between the two time periods for mean age (71 and 70 years (p=0.309)), sex distribution (males 70% and 71% (p=0.708)), location of the OHCA (home 64% and 63% (p=0.732)), proportion of shockable rhythms (44% and 47% (p=0.261)) and rate of return of spontaneous circulation (38% and 43% (p=0.136)), respectively. Bystander cardiopulmonary resuscitation (CPR), however, increased significantly from 60% to 73% (p<0.0001), as did the overall rate of survival to discharge from 18% to 25% (p=0.018). In patients with a shockable first rhythm, rate of survival to discharge increased significantly from 37% to 48% (p=0.036). In witnessed arrest with shockable rhythm survival to discharge increased from 37% to 52% (p=0.0105).
Overall, good outcome is now achievable in every fourth resuscitation attempt and in every second resuscitation attempt when patients have a shockable rhythm. The reason for the better outcomes is most likely multi-factorial and linked to improvements in the local chain of survival.
院外心脏骤停(OHCA)是西方国家主要的死亡原因。我们希望研究在已经报告高存活率的地区,随着时间的推移,生存率的变化及其相关因素。
我们使用前瞻性收集的乌斯廷模板数据库来确定所有推定心源性 OHCA 成年患者的复苏尝试。我们纳入了 846 次复苏尝试,并将两个时间段(2001-2005 年与 2006-2008 年)的存活至出院与良好结局进行比较。
两个时间段的平均年龄(71 岁和 70 岁(p=0.309))、性别分布(男性 70%和 71%(p=0.708))、OHCA 地点(家庭 64%和 63%(p=0.732))、可除颤节律的比例(44%和 47%(p=0.261))和自主循环恢复率(38%和 43%(p=0.136))均无显著差异。然而,旁观者心肺复苏(CPR)从 60%显著增加到 73%(p<0.0001),存活率从 18%增加到 25%(p=0.018)。在可除颤的首次节律患者中,存活率从 37%显著增加到 48%(p=0.036)。在有可除颤节律的目击性骤停中,存活率从 37%增加到 52%(p=0.0105)。
总的来说,现在每四次复苏尝试中就有一次能获得良好的结局,当患者有可除颤节律时,每两次复苏尝试中就有一次能获得良好的结局。良好结局的原因很可能是多因素的,并与当地生存链的改善有关。