Maurer M, Henn V, Dittrich A, Hofmann A
PSIN - Psychologisches Institut für Beratung und Forschung, Zürich, Switzerland.
Eur Arch Psychiatry Clin Neurosci. 1990;240(1):1-4. doi: 10.1007/BF02190083.
A double-blind study was performed comparing 5 mg delta-9-tetrahydrocannabinol (THC) p.o., 50 mg codeine p.o., and placebo in a patient with spasticity and pain due to spinal cord injury. The three conditions were applied 18 times each in a randomized and balanced order. Delta-9-THC and codeine both had an analgesic effect in comparison with placebo. Only delta-9-THC showed a significant beneficial effect on spasticity. In the dosage of THC used no altered consciousness occurred.
进行了一项双盲研究，比较口服5毫克δ-9-四氢大麻酚（THC）、口服50毫克可待因和安慰剂对一名因脊髓损伤导致痉挛和疼痛的患者的效果。这三种情况以随机且均衡的顺序各应用18次。与安慰剂相比，δ-9-THC和可待因均具有镇痛作用。只有δ-9-THC对痉挛显示出显著的有益效果。在所使用的THC剂量下，未出现意识改变。
