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美国一株产 CTX-M-15 的 ST131 型大肠埃希菌导致死亡的社区传播。

Community transmission in the United States of a CTX-M-15-producing sequence type ST131 Escherichia coli strain resulting in death.

机构信息

Division of Infectious Diseases, Department of Medicine, Maine Medical Center, Portland, Maine, USA.

出版信息

J Clin Microbiol. 2011 Sep;49(9):3406-8. doi: 10.1128/JCM.00993-11. Epub 2011 Jul 13.

DOI:10.1128/JCM.00993-11
PMID:21752984
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3165609/
Abstract

A middle-aged woman developed fatal urosepsis due to a multidrug-resistant Escherichia coli strain representing sequence type ST131, a recently emerged, disseminated, multidrug-resistant extraintestinal pathogen, after presumably having acquired it from her extensively antibiotic-exposed sister with chronic recurrent cystitis. Susceptibility results (reported on day 4) showed resistance to the initially selected regimen.

摘要

一名中年女性因一株携带 ST131 序列型的多药耐药型大肠杆菌而发生致命性尿路脓毒血症，该菌为新近出现的、广泛传播的、多重耐药的肠外病原体，推测该女性从其患有慢性复发性膀胱炎且广泛使用抗生素的姐姐处获得。药敏试验结果（第 4 天报告）显示最初选择的治疗方案耐药。

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Escherichia coli O25b-ST131: a pandemic, multiresistant, community-associated strain.大肠杆菌 O25b-ST131：一种流行的、多药耐药的、社区相关的菌株。
J Antimicrob Chemother. 2011 Jan;66(1):1-14. doi: 10.1093/jac/dkq415. Epub 2010 Nov 16.
2
Escherichia coli sequence type ST131 as the major cause of serious multidrug-resistant E. coli infections in the United States.大肠杆菌序列型 ST131 是导致美国严重的多药耐药大肠杆菌感染的主要原因。
Clin Infect Dis. 2010 Aug 1;51(3):286-94. doi: 10.1086/653932.
3
Molecular epidemiology of Escherichia coli producing CTX-M beta-lactamases: the worldwide emergence of clone ST131 O25:H4.产 CTX-M 型β-内酰胺酶大肠埃希菌的分子流行病学研究：ST131 O25:H4 克隆在全球的出现。
Int J Antimicrob Agents. 2010 Apr;35(4):316-21. doi: 10.1016/j.ijantimicag.2009.11.003. Epub 2010 Jan 13.
4
Within-household sharing of a fluoroquinolone-resistant Escherichia coli sequence type ST131 strain causing pediatric osteoarticular infection.耐氟喹诺酮的大肠杆菌 ST131 序列型菌株在家庭内的传播导致儿科骨关节炎感染。
Pediatr Infect Dis J. 2010 May;29(5):473-5. doi: 10.1097/INF.0b013e3181c89bd7.
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Escherichia coli sequence type ST131 as an emerging fluoroquinolone-resistant uropathogen among renal transplant recipients.大肠埃希菌序列型 ST131 作为一种新兴的耐氟喹诺酮类药物的尿路病原体，在肾移植受者中。
Antimicrob Agents Chemother. 2010 Jan;54(1):546-50. doi: 10.1128/AAC.01089-09. Epub 2009 Nov 16.
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