Public Health and Preventive Medicine program, Dalla Lana School of Public Health, University of Toronto, Ontario.
Can Fam Physician. 2011 Jul;57(7):e253-62.
To examine the applicability of 10 common clinical practice guidelines (CPGs) to elderly patients with multiple comorbidities.
Content analysis of published Canadian CPGs for the following chronic diseases: diabetes, dyslipidemia, dementia, congestive heart failure, depression, osteoporosis, hypertension, gastroesophageal reflux disease, chronic obstructive pulmonary disease, and osteoarthritis.
Presence or absence of 4 key indicators of applicability of CPGs to elderly patients with multiple comorbidities. These indicators include any mention of older adults or people with comorbidities, time needed to treat to benefit in the context of life expectancy, and barriers to implementation of the CPG.
Out of the 10 CPGs reviewed, 7 mentioned treatment of the elderly, 8 mentioned people with comorbidities, 4 indicated the time needed to treat to benefit in the context of life expectancy, 5 discussed barriers to implementation, and 7 discussed the quality of evidence.
This study shows that although most CPGs discuss the elderly population, only a handful of them adequately address issues related to elderly patients with comorbidities. In order to make CPGs more patient centred rather than disease driven, guideline developers should include information on elderly patients with comorbidities.
研究 10 项常见临床实践指南(CPG)在患有多种合并症的老年患者中的适用性。
对以下慢性疾病的已发表加拿大 CPG 进行内容分析:糖尿病、血脂异常、痴呆、充血性心力衰竭、抑郁、骨质疏松症、高血压、胃食管反流病、慢性阻塞性肺疾病和骨关节炎。
CPG 对患有多种合并症的老年患者适用性的 4 个关键指标的存在或缺失。这些指标包括是否提及老年人或合并症患者、在预期寿命背景下治疗获益所需的时间,以及 CPG 实施的障碍。
在审查的 10 项 CPG 中,有 7 项提及了老年患者的治疗,8 项提及了合并症患者,4 项表明了在预期寿命背景下治疗获益所需的时间,5 项讨论了实施障碍,7 项讨论了证据质量。
本研究表明,尽管大多数 CPG 都讨论了老年人群,但只有少数 CPG 充分解决了与患有合并症的老年患者相关的问题。为了使 CPG 更以患者为中心而不是以疾病为导向,指南制定者应包括患有合并症的老年患者的信息。