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骨质疏松症筛查和治疗指南:是否得到遵循?

Osteoporosis screening and treatment guidelines: are they being followed?

机构信息

The Reading Hospital and Medical Center, Department of ObGyn, Reading, PA 19612-6052, USA.

出版信息

Menopause. 2011 Oct;18(10):1072-8. doi: 10.1097/gme.0b013e318215101a.

DOI:10.1097/gme.0b013e318215101a
PMID:21753740
Abstract

OBJECTIVE

The objective of this study was to examine a cohort of women sent for dual-energy x-ray absorptiometry (DXA) screening to see whether they met the criteria for bone density testing. In addition, we sought to determine whether they were receiving appropriate interventions, based on published guidelines.

METHODS

Between January 1, 2007, and March 1, 2009, inclusive, postmenopausal women (age >49 y) who were sent for DXA bone density screening were offered enrollment into the study. Risk factors for osteoporosis, demographic information, and current DXA results were recorded. The 2006 Osteoporosis Position Statement of The North American Menopause Society was used for screening and therapeutic intervention guidelines.

RESULTS

Among the 615 women with data, the mean (SD) age was 61.5 (8.3) years. Using the 2006 guidelines of The North American Menopause Society, 41.3% (253 of 612) of the women who had DXA testing did not meet the criteria for such screening. Of these women, 25.5% (157 of 615) were not taking calcium, 31.1% (191 of 614) were not taking vitamin D, and 59.8% (343 of 574) were not exercising at least half an hour per week. Of the women with any of the approved indications for treatment, 15.7% (16 of 102) were not taking calcium, 18.6% (19 of 102) were not taking vitamin D, 52.7% (49 of 93) were not exercising at least 2 hours per week, and 35.3% (36 of 102) were not receiving therapy. In contrast, of those women without an indication for treatment, 17.8% (83 of 467) were receiving bisphosphonate, raloxifene, or calcitonin therapy.

CONCLUSIONS

A large number of women are not properly screened or treated for osteoporosis. Inappropriate screening may also lead to improper management of osteoporosis and its associated complications.

摘要

目的

本研究旨在检查一组接受双能 X 射线吸收法(DXA)筛查的女性,以确定她们是否符合骨密度检测标准。此外,我们还根据已发表的指南,试图确定她们是否接受了适当的干预措施。

方法

2007 年 1 月 1 日至 2009 年 3 月 1 日期间,对接受 DXA 骨密度筛查的绝经后女性(年龄>49 岁)进行了入组。记录了骨质疏松症的风险因素、人口统计学信息和当前的 DXA 结果。本研究使用了 2006 年北美绝经学会的骨质疏松症立场声明来进行筛查和治疗干预指南。

结果

在 615 名有数据的女性中,平均(标准差)年龄为 61.5(8.3)岁。根据 2006 年北美绝经学会的指南,41.3%(253/612)接受 DXA 检测的女性不符合筛查标准。在这些女性中,25.5%(157/615)未服用钙,31.1%(191/614)未服用维生素 D,59.8%(343/574)未每周至少进行半小时的运动。在有任何批准的治疗指征的女性中,15.7%(16/102)未服用钙,18.6%(19/102)未服用维生素 D,52.7%(49/93)未每周至少运动 2 小时,35.3%(36/102)未接受治疗。相比之下,在没有治疗指征的女性中,17.8%(83/467)正在接受双磷酸盐、雷洛昔芬或降钙素治疗。

结论

大量女性未接受适当的骨质疏松症筛查或治疗。不适当的筛查也可能导致骨质疏松症及其相关并发症的不当管理。

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