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N-（5-乙硫基-1,3,4-噻二唑-2-基）-2-（4,5,6,7-四氢噻吩并[3,2-c]吡啶-5-基）乙酰胺

N-(5-Ethylsulfanyl-1,3,4-thiadiazol-2-yl)-2-(4,5,6,7-tetrahydrothieno[3,2-c]pyri-din-5-yl)acetamide.

作者信息

Zhi Shuang, Mu Shuai, Liu Ying, Liu Deng-Ke

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 1;67(Pt 6):o1490. doi: 10.1107/S1600536811017107. Epub 2011 May 25.

DOI:10.1107/S1600536811017107
PMID:21754858
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3120429/
Abstract

In the title compound, C(13)H(16)N(4)OS(3), a thienopyridine-derivative, the tetra-hydro-pyridine ring exhibits a half-chair conformation, and the folded conformation of the mol-ecule is defined by the N-C-C-N torsion angle of -78.85 (16)°. The crystal packing features inter-molecular C-H⋯N, N-H⋯N and C-H⋯O hydrogen bonds.

摘要

在标题化合物C₁₃H₁₆N₄OS₃（一种噻吩并吡啶衍生物）中，四氢吡啶环呈半椅式构象，分子的折叠构象由-78.85 (16)°的N-C-C-N扭转角确定。晶体堆积具有分子间C-H⋯N、N-H⋯N和C-H⋯O氢键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b12/3120429/3a1058484ab3/e-67-o1490-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b12/3120429/82770714ac32/e-67-o1490-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b12/3120429/3a1058484ab3/e-67-o1490-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b12/3120429/82770714ac32/e-67-o1490-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b12/3120429/3a1058484ab3/e-67-o1490-fig2.jpg

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