• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

N-（5-硝基吡啶-2-基）-5H-二苯并[d,f][1,3]二氮杂䓬-6-甲酰胺

N-(5-Nitro-pyridin-2-yl)-5H-dibenzo[d,f][1,3]diazepine-6-carboxamide.

作者信息

Seidler Tomasz, Gryl Marlena, Trzewik Bartosz, Stadnicka Katarzyna

机构信息

Faculty of Chemistry, Jagiellonian University, R. Ingardena 3, 30-060 Kraków, Poland.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 1;67(Pt 6):o1507. doi: 10.1107/S1600536811018629. Epub 2011 May 25.

DOI:10.1107/S1600536811018629
PMID:21754873
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3120606/
Abstract

The title compound, C(19)H(13)N(5)O(3), can be obtained from the corresponding α-amido-α-amino-nitrone in a reaction with biphenyl-2,2'-diamine. The amido-amidine core has distinctive geometrical parameters including: an outstandingly long Csp(2)-Csp(2) single bond of 1.5276 (13) Å and an amidine N-C-N angle of 130.55 (9)°. Intra-molecular N-H⋯O, N-H⋯N and C-H⋯O hydrogen bonds occur. In the crystal, mol-ecules form layers parallel to (001) via weak inter-molecular C-H⋯N inter-actions. The layers are linked via N-H⋯O hydrogen bonds and π-π inter-actions along [001] [benzene-pyridine centroid-centroid distance = 3.672 (2) Å].

摘要

标题化合物C(19)H(13)N(5)O(3)可通过相应的α-酰胺基-α-氨基硝酮与联苯-2,2'-二胺反应得到。酰胺基脒核心具有独特的几何参数，包括：一条异常长的1.5276 (13) Å的Csp(2)-Csp(2)单键以及一个130.55 (9)°的脒N-C-N角。分子内存在N-H⋯O、N-H⋯N和C-H⋯O氢键。在晶体中，分子通过弱的分子间C-H⋯N相互作用形成平行于(001)的层。这些层通过N-H⋯O氢键和沿[001]的π-π相互作用相连[苯-吡啶质心-质心距离 = 3.672 (2) Å]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4bd/3120606/b1da99feb588/e-67-o1507-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4bd/3120606/1de989fb2588/e-67-o1507-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4bd/3120606/980e31ad4498/e-67-o1507-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4bd/3120606/de0637bc7354/e-67-o1507-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4bd/3120606/b1da99feb588/e-67-o1507-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4bd/3120606/1de989fb2588/e-67-o1507-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4bd/3120606/980e31ad4498/e-67-o1507-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4bd/3120606/de0637bc7354/e-67-o1507-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4bd/3120606/b1da99feb588/e-67-o1507-fig4.jpg

相似文献

1
N-(5-Nitro-pyridin-2-yl)-5H-dibenzo[d,f][1,3]diazepine-6-carboxamide.N-（5-硝基吡啶-2-基）-5H-二苯并[d,f][1,3]二氮杂䓬-6-甲酰胺
Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 1;67(Pt 6):o1507. doi: 10.1107/S1600536811018629. Epub 2011 May 25.
2
Crystal structures of N-(pyridin-2-ylmeth-yl)pyrazine-2-carboxamide (monoclinic polymorph) and N-(pyridin-4-ylmeth-yl)pyrazine-2-carboxamide.N-（吡啶-2-基甲基）吡嗪-2-甲酰胺（单斜晶多晶型物）和N-（吡啶-4-基甲基）吡嗪-2-甲酰胺的晶体结构
Acta Crystallogr Sect E Struct Rep Online. 2014 Jun 23;70(Pt 7):18-22. doi: 10.1107/S1600536814009519. eCollection 2014 Jul 1.
3
2-Amino-benzoic acid-4-(pyridin-4-yl-disulfan-yl)pyridine (1/1).2-氨基苯甲酸-4-(吡啶-4-基-二硫烷基)吡啶(1/1)
Acta Crystallogr Sect E Struct Rep Online. 2011 Dec 1;67(Pt 12):o3361. doi: 10.1107/S1600536811048483. Epub 2011 Nov 19.
4
Crystal structures of isomeric 3,5-di-chloro--(2,3-di-methyl-phen-yl)benzene-sulfonamide, 3,5-di-chloro--(2,6-di-methyl-phen-yl)benzene-sulfonamide and 3,5-di-chloro--(3,5-di-methyl-phen-yl)benzene-sulfonamide.同分异构体3,5-二氯-γ-(2,3-二甲基苯基)苯磺酰胺、3,5-二氯-γ-(2,6-二甲基苯基)苯磺酰胺和3,5-二氯-γ-(3,5-二甲基苯基)苯磺酰胺的晶体结构
Acta Crystallogr E Crystallogr Commun. 2017 Apr 11;73(Pt 5):673-677. doi: 10.1107/S2056989017005230. eCollection 2017 May 1.
5
Crystal structures and Hirshfeld surface analyses of 2-[(4,6-di-amino-pyrimidin-2-yl)sulfan-yl]--(pyridin-2-yl)acetamide and 2-[(4,6-di-amino-pyrimidin-2-yl)sulfan-yl]--(pyrazin-2-yl)acetamide.2-[(4,6-二氨基嘧啶-2-基)硫烷基]-(吡啶-2-基)乙酰胺和2-[(4,6-二氨基嘧啶-2-基)硫烷基]-(吡嗪-2-基)乙酰胺的晶体结构及 Hirshfeld 表面分析
Acta Crystallogr E Crystallogr Commun. 2018 Apr 27;74(Pt 5):718-723. doi: 10.1107/S2056989018005704. eCollection 2018 May 1.
6
Crystal structure of N-{4-[(6-chloro-pyridin-3-yl)meth-oxy]phen-yl}-2,6-di-fluoro-benzamide.N-{4-[(6-氯吡啶-3-基)甲氧基]苯基}-2,6-二氟苯甲酰胺的晶体结构
Acta Crystallogr E Crystallogr Commun. 2016 Jan 1;72(Pt 1):60-2. doi: 10.1107/S2056989015023701.
7
(E)-1-[(2-Amino-5-nitro-phen-yl)iminio-meth-yl]naphthalen-2-olate.（E）-1- [（2-氨基-5-硝基-苯基）亚氨基甲基]萘-2-醇盐
Acta Crystallogr Sect E Struct Rep Online. 2010 Apr 30;66(Pt 5):o1227-8. doi: 10.1107/S1600536810014923.
8
2-Amino-benzoic acid-4-[2-(pyridin-4-yl)eth-yl]pyridine (2/1).2-氨基苯甲酸-4-[2-(吡啶-4-基)乙基]吡啶(2/1)
Acta Crystallogr Sect E Struct Rep Online. 2013 Oct 5;69(Pt 11):o1616. doi: 10.1107/S1600536813027128.
9
(E)-N'-(3-Bromo-5-chloro-2-hy-droxy-benzyl-idene)nicotinohydrazide.（E）-N'-（3-溴-5-氯-2-羟基亚苄基）烟酰肼
Acta Crystallogr Sect E Struct Rep Online. 2011 Oct 1;67(Pt 10):o2716. doi: 10.1107/S1600536811038268. Epub 2011 Sep 30.
10
Crystal structure of 7-{[bis-(pyridin-2-ylmeth-yl)amino]-meth-yl}-5-chloro-quinolin-8-ol.7-{[双-(吡啶-2-基甲基)氨基]-甲基}-5-氯喹啉-8-醇的晶体结构
Acta Crystallogr E Crystallogr Commun. 2015 Nov 28;71(Pt 12):1545-7. doi: 10.1107/S2056989015022410. eCollection 2015 Dec 1.

引用本文的文献

1
Crystal structure of 2,2-dimethyl-N-(5-methyl-pyridin-2-yl)propanamide.2,2-二甲基-N-(5-甲基吡啶-2-基)丙酰胺的晶体结构
Acta Crystallogr E Crystallogr Commun. 2015 May 23;71(Pt 6):o419-20. doi: 10.1107/S2056989015009378. eCollection 2015 Jun 1.
2
Crystal structure of 2,2-dimethyl-N-(pyridin-3-yl)propanamide.2,2-二甲基-N-(吡啶-3-基)丙酰胺的晶体结构
Acta Crystallogr E Crystallogr Commun. 2015 Mar 21;71(Pt 4):o246-7. doi: 10.1107/S2056989015005289. eCollection 2015 Apr 1.
3
2,2-Dimethyl-N-(4-methyl-pyridin-2-yl)propanamide.

本文引用的文献

1
(2Z)-2-Anilino-2-[oxido(phen-yl)iminio]-N-(2-pyrid-yl)acetamide methanol 0.425-solvate.（2Z）-2-苯胺基-2-[氧化（苯基）亚氨基]-N-（2-吡啶基）乙酰胺甲醇0.425溶剂化物
Acta Crystallogr Sect E Struct Rep Online. 2008 Feb 15;64(Pt 3):o599-600. doi: 10.1107/S1600536808003346.
2
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
2,2-二甲基-N-(4-甲基吡啶-2-基)丙酰胺
Acta Crystallogr Sect E Struct Rep Online. 2014 Feb 26;70(Pt 3):o351-2. doi: 10.1107/S1600536814003729. eCollection 2014 Mar 1.