临床胰岛移植中白细胞功能抗原-1（LFA-1）的阻断 - Suppr

Suppr

超能文献

Blockade of leukocyte function antigen-1 (LFA-1) in clinical islet transplantation.

作者信息

Fotino Carmen, Pileggi Antonello

机构信息

Diabetes Research Institute, University of Miami, Miami, FL 33136, USA.

出版信息

Curr Diab Rep. 2011 Oct;11(5):337-44. doi: 10.1007/s11892-011-0214-y.

DOI:10.1007/s11892-011-0214-y

PMID:21755435

Abstract

摘要

相似文献

Blockade of leukocyte function antigen-1 (LFA-1) in clinical islet transplantation.临床胰岛移植中白细胞功能抗原-1（LFA-1）的阻断

Curr Diab Rep. 2011 Oct;11(5):337-44. doi: 10.1007/s11892-011-0214-y.

Perturbation of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 results in differential outcomes in cardiac vs islet allograft survival.白细胞功能相关抗原-1/细胞间黏附分子-1的扰动导致心脏与胰岛同种异体移植存活的不同结果。

J Heart Lung Transplant. 2005 Sep;24(9):1410-4. doi: 10.1016/j.healun.2004.09.004.

The effect of simultaneous CD154 and LFA-1 blockade on the survival of allogeneic islet grafts in nonobese diabetic mice.同时阻断CD154和淋巴细胞功能相关抗原-1对非肥胖糖尿病小鼠同种异体胰岛移植存活的影响。

Transplantation. 2003 Dec 27;76(12):1669-74. doi: 10.1097/01.TP.0000092525.17025.D0.

Prolongation of rat islet allograft survival by treatment with monoclonal antibodies against VLA-4 and LFA-1.通过用抗VLA-4和LFA-1单克隆抗体治疗延长大鼠胰岛同种异体移植物存活时间。

Transplantation. 1995 Jul 15;60(1):71-6. doi: 10.1097/00007890-199507150-00014.

Impact of Leukocyte Function-Associated Antigen-1 Blockade on Endogenous Allospecific T Cells to Multiple Minor Histocompatibility Antigen Mismatched Cardiac Allograft.白细胞功能相关抗原-1 阻断对多种次要组织相容性抗原不匹配心脏移植物内源性同种异体 T 细胞的影响。

Transplantation. 2015 Dec;99(12):2485-93. doi: 10.1097/TP.0000000000000805.

ICAM-1 antisense oligodeoxynucleotide improves islet allograft survival and function.细胞间黏附分子-1反义寡脱氧核苷酸可提高胰岛移植存活率及功能。

Cell Transplant. 2000 Nov-Dec;9(6):817-28. doi: 10.1177/096368970000900608.

Effect of triple costimulation blockade on islet allograft survival in sensitized mice.三联共刺激阻断对致敏小鼠胰岛同种异体移植存活的影响。

Transplant Proc. 2010 Jul-Aug;42(6):2109-11. doi: 10.1016/j.transproceed.2010.05.084.

Anti-LFA-1 improves pig islet xenograft function in diabetic mice when long-term acceptance is induced by CTLA4Ig/anti-CD40L.当通过CTLA4Ig/抗CD40L诱导长期接受时，抗淋巴细胞功能相关抗原-1可改善糖尿病小鼠的猪胰岛异种移植功能。

Transplantation. 2007 May 15;83(9):1259-67. doi: 10.1097/01.tp.0000261722.02697.75.

Indefinite survival of neonatal porcine islet xenografts by simultaneous targeting of LFA-1 and CD154 or CD45RB.通过同时靶向淋巴细胞功能相关抗原-1（LFA-1）和CD154或CD45RB实现新生猪胰岛异种移植的长期存活

Diabetes. 2005 Feb;54(2):443-51. doi: 10.2337/diabetes.54.2.443.

Induction of unresponsiveness to islet xenograft by MMC treatment of graft and blockage of LFA-1/ICAM-1 pathway.通过丝裂霉素C处理移植物及阻断淋巴细胞功能相关抗原-1/细胞间黏附分子-1途径诱导对胰岛异种移植物的无反应性

Transplantation. 2000 Apr 27;69(8):1567-71. doi: 10.1097/00007890-200004270-00008.

引用本文的文献

The impact of cell surface PEGylation and short-course immunotherapy on islet graft survival in an allogeneic murine model.细胞表面聚乙二醇化修饰及短期免疫治疗对同种异体小鼠模型胰岛移植存活的影响

Acta Biomater. 2017 Feb;49:272-283. doi: 10.1016/j.actbio.2016.11.060. Epub 2016 Nov 30.

Impact of Immune-Modulatory Drugs on Regulatory T Cell.免疫调节药物对调节性T细胞的影响。

Transplantation. 2016 Nov;100(11):2288-2300. doi: 10.1097/TP.0000000000001379.

Transdisciplinary approach to restore pancreatic islet function.跨学科方法恢复胰岛功能。

Immunol Res. 2013 Dec;57(1-3):210-21. doi: 10.1007/s12026-013-8437-4.

本文引用的文献

LFA-1-specific therapy prolongs allograft survival in rhesus macaques.LFA-1 特异性治疗可延长恒河猴同种异体移植物的存活时间。

J Clin Invest. 2010 Dec;120(12):4520-31. doi: 10.1172/JCI43895. Epub 2010 Nov 22.

Experience with a novel efalizumab-based immunosuppressive regimen to facilitate single donor islet cell transplantation.新型依维莫司为基础的免疫抑制方案在促进单供者胰岛细胞移植中的应用经验。

Am J Transplant. 2010 Sep;10(9):2082-91. doi: 10.1111/j.1600-6143.2010.03212.x.

Islet transplantation in type 1 diabetics using an immunosuppressive protocol based on the anti-LFA-1 antibody efalizumab.使用基于抗 LFA-1 抗体 efalizumab 的免疫抑制方案进行 1 型糖尿病的胰岛移植。

Am J Transplant. 2010 Aug;10(8):1870-80. doi: 10.1111/j.1600-6143.2010.03073.x.

Point: steady progress and current challenges in clinical islet transplantation.要点：临床胰岛移植的稳步进展与当前挑战

Diabetes Care. 2009 Aug;32(8):1563-9. doi: 10.2337/dc09-0490.

Stable renal function after islet transplantation: importance of patient selection and aggressive clinical management.胰岛移植后稳定的肾功能：患者选择及积极临床管理的重要性

Transplantation. 2009 Mar 15;87(5):681-8. doi: 10.1097/TP.0b013e31819279a8.

2008 Update from the Collaborative Islet Transplant Registry.来自协作胰岛移植登记处的2008年更新

Transplantation. 2008 Dec 27;86(12):1783-8. doi: 10.1097/TP.0b013e3181913f6a.

A multi-year analysis of islet transplantation compared with intensive medical therapy on progression of complications in type 1 diabetes.一项关于胰岛移植与强化药物治疗对1型糖尿病并发症进展影响的多年分析。

Transplantation. 2008 Dec 27;86(12):1762-6. doi: 10.1097/TP.0b013e318190b052.

Efalizumab: results of a 3-year continuous dosing study for the long-term control of psoriasis.依法利珠单抗：一项用于长期控制银屑病的3年持续给药研究结果

Br J Dermatol. 2008 May;158(5):1107-16. doi: 10.1111/j.1365-2133.2008.08548.x. Epub 2008 Mar 27.

Combination of anti-CD4 with anti-LFA-1 and anti-CD154 monoclonal antibodies promotes long-term survival and function of neonatal porcine islet xenografts in spontaneously diabetic NOD mice.抗CD4与抗LFA-1及抗CD154单克隆抗体联合使用可促进新生猪胰岛异种移植物在自发性糖尿病NOD小鼠体内长期存活并发挥功能。

Cell Transplant. 2007;16(8):787-98. doi: 10.3727/000000007783465244.

A phase I/II randomized open-label multicenter trial of efalizumab, a humanized anti-CD11a, anti-LFA-1 in renal transplantation.一项关于依法利珠单抗（一种人源化抗CD11a、抗淋巴细胞功能相关抗原-1）在肾移植中的I/II期随机开放标签多中心试验。

Am J Transplant. 2007 Jul;7(7):1770-7. doi: 10.1111/j.1600-6143.2007.01845.x.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验