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[着重于调节性T细胞在稳定眼部免疫学中的作用]

[Emphasis on the T regulatory cells in stabilizing immunology of the eye].

作者信息

Jie Ying, Pan Zhi-qiang

机构信息

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University;Beijing Ophthalmol & Visual Sciences Key Lab, Beijing 100730, China.

出版信息

Zhonghua Yan Ke Za Zhi. 2011 May;47(5):389-92.

Abstract

T regulatory cells (Tregs) have been recognized as the hotspot in recent immunology research. Because of the capability of immune suppression, they play an important role in regulating many immune associated diseases. It has been reported that they are involved in stabilizing local immune microenvironment of the eye and regulating many eye diseases such as corneal transplantation immune rejection, uveitis, allergic conjunctivitis, infectious keratitis and dry eye. Treatment with Tregs may provide novel method for immune related eye diseases.

摘要

调节性T细胞(Tregs)已成为近期免疫学研究的热点。由于其免疫抑制能力,它们在调节多种免疫相关疾病中发挥着重要作用。据报道,它们参与稳定眼部局部免疫微环境,并调节多种眼部疾病,如角膜移植免疫排斥反应、葡萄膜炎、过敏性结膜炎、感染性角膜炎和干眼症。用调节性T细胞进行治疗可能为免疫相关眼病提供新的方法。

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