Liang Deng-pan, Yao Xiao-guang, Li Nan-fang, Zhang De-lian, Guo Yan-ying, Lin Li, Zhou Ling, Li Wen-chang, Yan Zhi-tao, Wang Hong-mei, Luo Wen-li, Chang Jian-hang
Department of Hypertension, People's Hospital of Xinjiang Uygur Autonomous Region, The Center of Diagnosis, Treatment and Research of Hypertension in Xinjiang, Urumqi 830001, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2011 May;45(5):440-3.
To study the lipids level in Kazakan individuals over 30-year-old in Fukang area of Xinjiang.
Random cluster multistage sampling method were performed to select the subjects, and 991 individuals aged older than 30 from Fukang of Xinjiang were included. The plasma total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), plasma glucose and insulin were measured. Related adverse cardiovascular risk factors were discussed.
The mean plasma TC, TG, HDL-C and LDL-C of Kazakan residents over 30-year-old in Fukang of Xinjiang were (5.05 ± 1.07), (1.10 ± 0.66), (1.46 ± 0.38) and (3.06 ± 0.84) mmol/L, respectively. TC, TG and LDL-C levels in male subjects were higher than those in females (male vs female: TC: (5.19 ± 1.05) mmol/L vs (4.94 ± 1.07) mmol/L, t = 3.57, P < 0.01; TG: (1.32 ± 0.80) mmol/L vs (0.94 ± 0.46) mmol/L, t = 8.63, P < 0.01; LDL-C: (3.30 ± 0.85) mmol/L vs (2.88 ± 0.79) mmol/L, t = 8.06, P < 0.01). While the HDL-C level in male subjects was lower than that of female (male vs female: (1.32 ± 0.33) mmol/L vs (1.57 ± 0.38) mmol/L, t = 11.48, P < 0.01). The prevalence of dyslipidemia was 28.3% (280/991) in the overall populations. In the overall populations, the prevalence of hypercholesteremia, hypertriglyceridemia, high low-density lipoprotein cholesterolemia and low serum high density lipoprotein cholesterolemia were 12.6% (125/991), 6.6% (65/991), 11.0% (109/991) and 10.1% (100/991), respectively. The prevalence of individuals with borderline-high TC, TG and LDL-C were 27.0% (268/991), 7.6% (75/991) and 20.5% (203/991), respectively. The prevalence of dyslipidemia was 40.0% (172/430) in male populations. The prevalence of dyslipidemia in group aged 30 - 39, 40 - 49, 50 - 59, 60 and above were 26.2% (78/298), 26.0% (91/350), 31.2% (73/234) and 34.9% (38/109), respectively, the trend of prevalence was significant by trend test for groups comparison (χ(2) = 3.94, P < 0.05). Adjusting for age and gender, TG was positively correlated with waist circumference, abdominal circumference and BMI, the partial relation coefficients were 0.368 (P < 0.01), 0.336 (P < 0.01) and 0.331 (P < 0.01), respectively, and HDL-C was negatively correlated with waist circumference, abdominal circumference and BMI, the partial relation coefficients were -0.340 (P < 0.01), -0.339 (P < 0.01) and -0.321 (P < 0.01), respectively.
The lipid levels of Kazakan residents from Fukang area are high and are characterized by hypercholesteremia and high low-density lipoprotein cholesterolemia, and more attention of the prevention of dyslipidemia in this populations should be paid to males, border-line abnormal and those aged over 60-year old.
研究新疆阜康地区30岁以上哈萨克族人群血脂水平。
采用随机整群多级抽样方法选取研究对象，纳入991名来自新疆阜康的30岁以上人群。检测血浆总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）、血糖和胰岛素水平，并探讨相关心血管不良危险因素。
新疆阜康30岁以上哈萨克族居民血浆TC、TG、HDL-C和LDL-C均值分别为（5.05±1.07）、（1.10±0.66）、（1.46±0.38）和（3.06±0.84）mmol/L。男性受试者的TC、TG和LDL-C水平高于女性（男性与女性比较：TC：（5.19±1.05）mmol/L对（4.94±1.07）mmol/L，t=3.57，P<0.01；TG：（1.32±0.80）mmol/L对（0.94±0.46）mmol/L，t=8.63，P<0.01；LDL-C：（3.30±0.85）mmol/L对（2.88±0.79）mmol/L，t=8.06，P<0.01）。而男性受试者的HDL-C水平低于女性（男性与女性比较：（1.32±0.33）mmol/L对（1.57±0.38）mmol/L，t=11.48，P<0.01）。总体人群中血脂异常患病率为28.3%（280/991）。总体人群中，高胆固醇血症、高甘油三酯血症、高低密度脂蛋白胆固醇血症和低血清高密度脂蛋白胆固醇血症的患病率分别为12.6%（125/991）、6.6%（65/991）、11.0%（109/991）和10.1%（100/991）。TC、TG和LDL-C边缘升高个体的患病率分别为27.0%（268/991）、7.6%（75/991）和20.5%（203/991）。男性人群中血脂异常患病率为40.0%（172/430）。3039岁、4049岁、50~59岁、60岁及以上组血脂异常患病率分别为26.2%（78/298）、26.0%（91/350）、31.2%（73/234）和34.9%（38/109），组间比较趋势检验显示患病率趋势有统计学意义（χ(2)=3.94，P<0.05）。校正年龄和性别后，TG与腰围、腹围和BMI呈正相关，偏相关系数分别为0.368（P<0.01）、0.336（P<0.01）和0.331（P<0.01），HDL-C与腰围、腹围和BMI呈负相关，偏相关系数分别为-0.340（P<0.01）、-0.339（P<0.01）和-0.321（P<0.01）。
新疆阜康地区哈萨克族居民血脂水平偏高，以高胆固醇血症和高低密度脂蛋白胆固醇血症为特点，该人群血脂异常的防治应重点关注男性、边缘异常者及60岁以上人群。
