Department of Surgery, Division of Trauma Surgery and Orthopaedic Surgery, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstr. 12, 91054 Erlangen, Germany.
Int Orthop. 2012 Apr;36(4):719-22. doi: 10.1007/s00264-011-1321-8. Epub 2011 Jul 15.
The purpose of this study was to evaluate the use of negative pressure wound therapy (NPWT) to improve wound healing after total hip arthroplasty (THA) and its influence on the development of postoperative seromas in the wound area.
The study is a prospective randomised evaluation of NPWT in patients with large surgical wounds after THA, randomising patients to either a standard dressing (group A) or a NPWT (group B) over the wound area. The wound area was examined with ultrasound to measure the postoperative seromas in both groups on the fifth and tenth postoperative days.
There were 19 patients randomised in this study. Ten days after surgery, group A (ten patients, 70.5 ± 11.01 years of age) developed seromas with an average size of 5.08 ml and group B (nine patients, 66.22 ± 17.83 years of age) 1.97 ml. The difference was significant (p = 0.021).
NPWT has been used on many different types of traumatic and non traumatic wounds. This prospective, randomised study has demonstrated decreased development of postoperative seromas in the wound and improved wound healing.
本研究旨在评估负压伤口治疗（NPWT）在全髋关节置换术后改善伤口愈合的效果，及其对伤口区域术后血清肿形成的影响。
本研究为前瞻性随机评估 NPWT 在全髋关节置换术后大手术伤口患者中的应用，将患者随机分为标准敷料组（A 组）或 NPWT 组（B 组）覆盖伤口区域。在术后第 5 天和第 10 天，使用超声检查两组患者的伤口区域，以测量术后血清肿。
本研究共纳入 19 名患者。术后 10 天，A 组（10 例，70.5 ± 11.01 岁）出现血清肿，平均大小为 5.08 ml，B 组（9 例，66.22 ± 17.83 岁）为 1.97 ml。差异有统计学意义（p = 0.021）。
NPWT 已被用于多种不同类型的创伤性和非创伤性伤口。这项前瞻性、随机研究表明，NPWT 可减少术后血清肿的形成，促进伤口愈合。
