Zak Małgorzata, Kuropka Piotr, Kobielarz Magdalena, Dudek Agnieszka, Kaleta-Kuratewicz Katarzyna, Szotek Sylwia
Division of Biomedical Engineering and Experimental Mechanics, Wrocław University of Technology, Poland.
Acta Bioeng Biomech. 2011;13(2):37-43.
Skin is an important barrier protecting the organism against external environmental factors. Determination of its mechanical characteristics as regards its structure has significant scientific and application value. In this work, uniaxial tensile tests were conducted to determine the basic mechanical parameters of skin with respect to its structure. The subject of the study were skin samples taken from domestic pig foetuses. They were excised from different parts of body, in the direction parallel to the long axis of the body. Regardless of the sampling site, the tests revealed no significant differences in the values of the maximum tensile strength (2.08 ± 0.25 MPa) and the conventional Young's modulus (5.87 ± 1.52 MPa). The mechanical and structural tests confirmed that regardless of the sampling region the skin of domestic pig foetuses may constitute a human skin substitute model.
皮肤是保护机体免受外部环境因素影响的重要屏障。确定其结构方面的力学特性具有重要的科学和应用价值。在这项工作中,进行了单轴拉伸试验以确定皮肤结构方面的基本力学参数。研究对象是取自家猪胎儿的皮肤样本。它们从身体的不同部位沿平行于身体长轴的方向切除。无论取样部位如何,试验均表明最大拉伸强度值(2.08±0.25兆帕)和常规杨氏模量值(5.87±1.52兆帕)没有显著差异。力学和结构测试证实,无论取样区域如何,家猪胎儿的皮肤都可以构成人类皮肤替代模型。