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经尿道中段吊带术治疗女性压力性尿失禁对女性性功能的影响:一项多中心前瞻性研究。

The impact of mid-urethral slings for the treatment of urodynamic stress incontinence on female sexual function: a multicenter prospective study.

机构信息

Section of Urology, S.S. Annunziata Hospital, Savigliano, Cuneo, Italy.

出版信息

J Sex Med. 2011 Jul;8(7):2002-8. doi: 10.1111/j.1743-6109.2011.02278.x.

DOI:10.1111/j.1743-6109.2011.02278.x
PMID:21762389
Abstract

INTRODUCTION

Urinary incontinence is a common condition that negatively impacts on female sexuality (FS).

AIM

To evaluate FS before and after a mid-urethral sling (MUS) procedure using the Female Sexual Function Index (FSFI). We included women that were both sexually and nonsexually active at baseline.

METHODS

One hundred fifty-seven women complaining of urodynamic stress incontinence underwent a MUS procedure and were enrolled in the study. All patients answered the Italian translation of FSFI, before and 12 months after surgery. To understand the real impact of the MUS on female sexual function, for the first time in the literature, we also monitored and included in the final analysis all the women who are nonsexually active at baseline. We evaluated the prevalence of female sexual dysfunction according to the FSFI cutoff point (26.55).

MAIN OUTCOME MEASURES

FSFI total score, pads use, and stress test presurgery and postsurgery.

RESULTS

One hundred thirty-three patients completed the study protocol: 105 out of 133 underwent to a trans-obturator procedure, while 28 out of 133 had a retropubic procedure. After the 12-month follow up, 115 out of 133 patients (86%) were dry, 10 improved their symptoms, and the remaining 8 were unchanged. Seventy-nine out of 133 (59%) patients reported an active sexual life before surgery. Fifty-four (41%) reported they were not sexually active before surgery. Twelve months after surgery, 22 out of 54 nonsexually active women (40%) reestablished sexual activity, whereas only 6 out of 79 (7.5%) patients, sexually active at baseline, were not sexually active 1 year after surgery (P < 0.05). After adjusting for multiple testing, only age, menopause, and storage symptoms remained significantly correlated with the FSFI total score postsurgery as independent variables. Conclusions.  Our data showed that after a MUS procedure, female sexual function improves. We also found that a very relevant percentage of nonsexually active women reported renewed sexual activity after MUS.

摘要

介绍

尿失禁是一种常见的疾病,会对女性的性生活产生负面影响。

目的

使用女性性功能指数(FSFI)评估中尿道吊带(MUS)手术后女性的性生活。我们包括了基线时既有性生活又无性生活的女性。

方法

157 名患有尿动力学压力性尿失禁的女性接受了 MUS 手术并参与了研究。所有患者在手术前和手术后 12 个月都回答了 FSFI 的意大利语翻译。为了了解 MUS 对女性性功能的实际影响,我们首次在文献中还监测并包括了基线时无性生活的所有女性,并将其纳入最终分析。我们根据 FSFI 截断值(26.55)评估女性性功能障碍的患病率。

主要观察指标

FSFI 总分、使用护垫和术前、术后压力试验。

结果

133 名患者完成了研究方案:133 名患者中有 105 名接受了经闭孔手术,28 名接受了经耻骨后手术。12 个月随访后,133 名患者中有 115 名(86%)干燥,10 名症状改善,其余 8 名无变化。79 名患者(59%)在手术前报告有活跃的性生活。54 名患者(41%)在手术前没有性生活。手术后 12 个月,54 名无性生活的女性中有 22 名(40%)重新开始性生活,而 79 名基线时有性生活的患者中只有 6 名(7.5%)在手术后 1 年内没有性生活(P<0.05)。在调整了多次测试后,只有年龄、绝经和储存症状与术后 FSFI 总分仍呈显著相关,是独立变量。结论。我们的数据显示,MUS 手术后女性的性功能得到改善。我们还发现,相当大比例的无性生活女性在 MUS 后报告恢复了性生活。

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