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TVT-SECUR 手术治疗女性压力性尿失禁对生活质量和性功能的短期影响。

Short-term effect of TVT-SECUR procedure on quality of life and sexual function in women with stress urinary incontinence.

机构信息

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.

出版信息

J Minim Invasive Gynecol. 2013 Jul-Aug;20(4):455-9. doi: 10.1016/j.jmig.2013.01.006. Epub 2013 Mar 15.

DOI:10.1016/j.jmig.2013.01.006
PMID:23506715
Abstract

STUDY OBJECTIVE

To investigate whether patient quality of life and sexual function are improved after the tension-free vaginal tape SECUR (TVT-S) procedure (H-type).

DESIGN

Prospective study (Canadian Task Force classification II-3).

SETTING

Single-center hospital.

PATIENTS

Thirty-three women with stress urinary incontinence (SUI) (high urethral mobility) and no concomitant pelvic floor prolapse underwent TVT-S between October 2009 and October 2011.

INTERVENTION

TVT-S procedure.

MEASUREMENTS AND MAIN RESULTS

Before and after surgery(6 and 12 months), all patients completed the Chinese version of the Incontinence Quality of Life Questionnaire (I-QOL). In addition, 28 sexually active patients who underwent the TVT-S procedure completed the short-form Pelvic Organ Prolapse/Urinary Incontinence Sexual Function Questionnaire (PISQ-12) before and after surgery (6 and 12 months). We used a paired t test to compare I-QOL scores before and after surgery. The Wilcoxon signed-rank test was used to compare the preoperative and postoperative PISQ scores. The objective cure rate was 78% (26 of 33 patients) at 12 months after surgery. The objective improvement rate was 12.1% (4 of 33 patients). The subjective satisfaction rate was 90%. Three operations (9.1%) were considered failures. Two patients underwent a TVT procedure after TVT-S because of recurrence. No patients reported severe pain; the mean (SD) visual analog scale pain score was 1.8 (1.2) after surgery. Only 1 patient (3%) was found to have sling erosion at 12 months postoperatively. The I-QOL score was 28.3 (14.2) before surgery and increased to 69.5 (18.9) at 12 months after the TVT-S procedure. The I-QOL score improved significantly after surgery (p <.001). The total PISQ-12 score at 6 months after surgery in all sexually active patients was 33.82 (0.87), compared with 31.57 (1.20) before surgery (p <.05). Physical domain scores on the PISQ-12 demonstrated significant improvement, increasing from 12.61 (0.75) to 14.36 (0.49) (p <.05). No significant difference was found between I-QOL and PISQ-12 scores at 6 and 12 months after surgery. There was no significant difference in total PISQ-12 scores in premenopausal patients before and after surgery (p >.05).

CONCLUSIONS

Although the objective cure rate was not high, the TVT-S procedure is a minimally invasive, safe, and effective surgical procedure for treatment of SUI (high urethral mobility) and can improve the quality of life and sexual function in women with SUI.

摘要

研究目的

探讨经阴道无张力悬吊带 SECUR(TVT-S)术(H 型)治疗后患者生活质量和性功能是否得到改善。

设计

前瞻性研究(加拿大卫生研究院分级 II-3 级)。

地点

单中心医院。

患者

2009 年 10 月至 2011 年 10 月期间,33 例压力性尿失禁(SUI)(尿道高移动度)且无合并盆腔器官脱垂的女性患者接受了 TVT-S 术。

干预措施

TVT-S 术。

测量和主要结果

所有患者在术前和术后(6 个月和 12 个月)均完成了中文版尿失禁生活质量问卷(I-QOL)。此外,28 例接受 TVT-S 术的有性生活史的患者在术前和术后(6 个月和 12 个月)完成了简短型盆腔器官脱垂/尿失禁性功能问卷(PISQ-12)。我们采用配对 t 检验比较手术前后 I-QOL 评分。采用 Wilcoxon 符号秩检验比较术前和术后 PISQ 评分。12 个月时的客观治愈率为 78%(33 例患者中的 26 例)。客观改善率为 12.1%(33 例患者中的 4 例)。主观满意度为 90%。3 例手术(9.1%)被认为失败。2 例患者因复发接受了 TVT 术。无患者报告严重疼痛;术后平均(SD)视觉模拟量表疼痛评分 1.8(1.2)。仅 1 例患者(3%)在术后 12 个月发现吊带侵蚀。I-QOL 评分术前为 28.3(14.2),TVT-S 术后 12 个月增至 69.5(18.9)。术后 I-QOL 评分显著改善(p<0.001)。所有有性生活史的患者术后 6 个月的总 PISQ-12 评分为 33.82(0.87),术前为 31.57(1.20)(p<0.05)。PISQ-12 的生理领域评分显著改善,从 12.61(0.75)增加到 14.36(0.49)(p<0.05)。术后 6 个月和 12 个月时,I-QOL 和 PISQ-12 评分之间无显著差异。术前和术后,绝经前患者的总 PISQ-12 评分无显著差异(p>0.05)。

结论

尽管客观治愈率不高,但 TVT-S 术是一种微创、安全且有效的治疗 SUI(尿道高移动度)的手术方法,可改善 SUI 女性的生活质量和性功能。

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