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用雷美尔酮治疗谵妄:三例初步经验。

Treatment of delirium with ramelteon: initial experience in three patients.

机构信息

Department of Psychiatry, Osaka General Medical Center, Osaka, 558-8558, Japan.

出版信息

Gen Hosp Psychiatry. 2011 Jul-Aug;33(4):407-9. doi: 10.1016/j.genhosppsych.2011.03.013. Epub 2011 May 20.

DOI:10.1016/j.genhosppsych.2011.03.013
PMID:21762839
Abstract

OBJECTIVE

The aim of the present study was to determine the efficacy of ramelteon for treating delirium.

METHODS

Three patients were prescribed ramelteon for delirium. The severity of the delirium was assessed using the Japanese version of the Memorial Delirium Assessment Scale.

RESULTS

Memorial Delirium Assessment Scale scores improved after treatment with ramelteon in all cases.

CONCLUSION

These cases suggest that ramelteon may be beneficial in the treatment of delirium. Randomized controlled studies are needed to confirm the therapeutic benefits.

摘要

目的

本研究旨在确定雷美替胺治疗谵妄的疗效。

方法

为 3 例谵妄患者开了雷美替胺处方。使用日文版的《记忆谵妄评估量表》评估谵妄的严重程度。

结果

所有患者在使用雷美替胺治疗后,《记忆谵妄评估量表》评分均有改善。

结论

这些病例表明雷美替胺可能对治疗谵妄有益。需要开展随机对照研究来确认其治疗效果。

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Treatment of delirium with ramelteon: initial experience in three patients.用雷美尔酮治疗谵妄:三例初步经验。
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2
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Successfully treated delirium in an extremely elderly patient by switching from risperidone to ramelteon.通过将利培酮换成雷美替胺成功治疗了一名极度老年患者的谵妄。
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Sci Rep. 2020 Dec 15;10(1):21996. doi: 10.1038/s41598-020-79078-4.
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Effect of Suvorexant on Nocturnal Delirium in Elderly Patients with Alzheimer's Disease: A Case-series Study.苏沃雷生对老年阿尔茨海默病患者夜间谵妄的影响:一项病例系列研究
Clin Psychopharmacol Neurosci. 2019 Nov 20;17(4):547-550. doi: 10.9758/cpn.2019.17.4.547.
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Clinical Practice Guidelines for Management of Delirium in Elderly.
老年人谵妄管理临床实践指南
Indian J Psychiatry. 2018 Feb;60(Suppl 3):S329-S340. doi: 10.4103/0019-5545.224473.
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Melatonin and the Prevention and Management of Delirium: A Scoping Study.褪黑素与谵妄的预防和管理:一项范围综述研究。
Front Med (Lausanne). 2018 Jan 8;4:242. doi: 10.3389/fmed.2017.00242. eCollection 2017.
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Exogenous Melatonin for Delirium Prevention: a Meta-analysis of Randomized Controlled Trials.外源性褪黑素预防谵妄的 Meta 分析:随机对照试验。
Mol Neurobiol. 2016 Aug;53(6):4046-4053. doi: 10.1007/s12035-015-9350-8. Epub 2015 Jul 21.
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Adjunctive treatment with melatonin receptor agonists for older delirious patients with the sundowning phenomenon.褪黑素受体激动剂对有日落现象的老年谵妄患者的辅助治疗。
J Psychiatry Neurosci. 2015 Mar;40(2):E25-6. doi: 10.1503/jpn.140166.
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Am J Alzheimers Dis Other Demen. 2015 Mar;30(2):119-29. doi: 10.1177/1533317514539379. Epub 2014 Jun 18.
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