头戴式高速相机，用于光学神经记录。
Head-mountable high speed camera for optical neural recording.
机构信息
School of Engineering and Applied Science, Yale University, New Haven, CT 06520, USA.
出版信息
J Neurosci Methods. 2011 Oct 15;201(2):290-5. doi: 10.1016/j.jneumeth.2011.06.024. Epub 2011 Jul 6.
Abstract
We report a head-mountable CMOS camera for recording rapid neuronal activity in freely moving rodents using fluorescent activity reporters. This small, lightweight camera is capable of detecting small changes in light intensity (0.2% ΔI/I) at 500fps. The camera has a resolution of 32×32, sensitivity of 0.62V/lxs, conversion gain of 0.52μV/e(-) and well capacity of 2.1Me(-). The camera, containing intensity offset subtraction circuitry within the imaging chip, is part of a miniaturized epi-fluorescent microscope and represents a first generation, mobile scientific-grade, physiology imaging camera.
摘要
我们报告了一款可头戴式的 CMOS 相机，用于使用荧光活性报告器记录自由活动的啮齿动物中的快速神经元活动。这款小巧、轻便的相机能够以 500fps 的速度检测到光强的微小变化（0.2%ΔI/I）。该相机的分辨率为 32×32，灵敏度为 0.62V/lxs，转换增益为 0.52μV/e(-)，阱容量为 2.1Me(-)。该相机在成像芯片内包含强度偏移减法电路，是微型化的 epi-荧光显微镜的一部分，代表了第一代移动的科学级生理成像相机。
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