Program in Cancer Biology, Stanford University, Stanford, CA 94305, USA.
Dev Cell. 2011 Jul 19;21(1):32-4. doi: 10.1016/j.devcel.2011.06.004.
Studies of animal evolution often focus on sequence and transcriptional analysis, based on an assumption that the evolution of development is driven by changes in gene expression. We argue that biochemical and cell biological approaches are also required, because sequence-conserved proteins can have different biochemical, cellular, and developmental properties.
动物进化的研究通常集中在序列和转录分析上,这是基于这样一个假设,即发育的进化是由基因表达的变化驱动的。我们认为,还需要生化和细胞生物学方法,因为序列保守的蛋白质可能具有不同的生化、细胞和发育特性。