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富含生长因子的血浆在再生医学中的应用:观点与挑战。

Perspectives and challenges in regenerative medicine using plasma rich in growth factors.

机构信息

Private Practice in Implantology and Oral Rehabilitation in Vitoria, Spain.

出版信息

J Control Release. 2012 Jan 10;157(1):29-38. doi: 10.1016/j.jconrel.2011.07.004. Epub 2011 Jul 8.

DOI:10.1016/j.jconrel.2011.07.004
PMID:21763737
Abstract

Plasma rich in growth factors (PRGF-Endoret) is an endogenous therapeutic technology that is gaining interest in regenerative medicine due to its potential to stimulate and accelerate tissue healing and bone regeneration. This autologous biotechnology is designed for the in situ delivery of multiple cellular modulators and the formation of a fibrin scaffold, thereby providing different formulations that can be widely used in numerous medical and scientific fields including dentistry, oral implantology, orthopedics, ulcer treatment and tissue engineering among others. Here we discuss the important progress that has been accomplished in this field. Furthermore, a comprehensive outlook of the intriguing therapeutic applications of this technology is presented.

摘要

富含生长因子的血浆 (PRGF-Endoret) 是一种内源性治疗技术,由于其具有刺激和加速组织愈合和骨再生的潜力,因此在再生医学领域引起了关注。这种自体生物技术旨在原位递送多种细胞调节剂并形成纤维蛋白支架,从而提供可广泛应用于众多医学和科学领域的不同配方,包括牙科、口腔种植学、骨科、溃疡治疗和组织工程等。在这里,我们讨论了该领域取得的重要进展。此外,还介绍了该技术引人入胜的治疗应用的全面展望。

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