Department of Otolaryngology-Head and Neck Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Am J Otolaryngol. 2012 Jan-Feb;33(1):188-91. doi: 10.1016/j.amjoto.2011.05.003. Epub 2011 Jul 20.
Extranodal natural killer/T-cell lymphoma of the nasal cavity is a rare malignancy with poor overall prognosis. We report the case of a rapidly fatal natural killer/T-cell lymphoma of the nasal cavity complicated by the concominant development of hemophagocytic lymphohistiocytosis. This disorder is marked by clinical findings such as fever and splenomegaly, a multitude of abnormal laboratory findings, and a profound proliferation of circulating macrophages. Left untreated, multi-organ failure and death are common. Prompt diagnosis is essential to the successful management of this disorder and for subsequent recovery.
鼻腔非霍奇金 NK/T 细胞淋巴瘤是一种罕见的恶性肿瘤，总体预后较差。我们报告了一例鼻腔 NK/T 细胞淋巴瘤迅速致命，并伴有噬血细胞性淋巴组织细胞增生症。这种疾病的特点是发热和脾肿大等临床症状，多种异常的实验室发现，以及循环巨噬细胞的大量增殖。如果不治疗，多器官衰竭和死亡很常见。及时诊断对于成功治疗这种疾病和随后的恢复至关重要。
