Department of Dermatology, China Medical University Hospital, Taichung, Taiwan.
Clin Exp Dermatol. 2009 Dec;34(8):e927-30. doi: 10.1111/j.1365-2230.2009.03714.x.
Extranodal natural killer (NK)/T-cell lymphoma, nasal type (ENKTLN), is characterized by higher prevalence in East Asians and South Americans, association with Epstein-Barr virus infection, aggressive nature in most cases, and resistance to conventional treatment strategies such as chemotherapy and radiotherapy. The optimum treatment for this disease has not yet been established. We report a successful treatment experience in a case of ENKTLN, with a combination regimen including interferon-alpha, corticosteroid and narrowband ultraviolet B, which may serve as a promising therapy for this aggressive disease at earlier stages.
结外自然杀伤（NK）/T 细胞淋巴瘤，鼻型（ENKTLN）的特点是在东亚和南美洲更为普遍，与 EBV 感染相关，大多数情况下侵袭性较强，对化疗和放疗等常规治疗策略具有耐药性。目前尚未确定该病的最佳治疗方法。我们报告了一例 ENKTLN 成功治疗的经验，采用包括干扰素-α、皮质类固醇和窄谱中波紫外线联合的治疗方案，这可能为早期侵袭性疾病提供一种有前途的治疗方法。
