Le Noël A, Mérat S, Ausset S, De Rudnicki S, Mion G
Département d'anesthésie-réanimation, hôpital d'instruction des armées du Val-de-Grâce, 74, boulevard de Port-Royal, 75230 Paris cedex 05, France.
Ann Fr Anesth Reanim. 2011 Sep;30(9):665-78. doi: 10.1016/j.annfar.2011.05.016. Epub 2011 Jul 20.
Damage control is a strategy of care for bleeding trauma patients, involving minimal rescue surgery associated to perioperative resuscitation. The purpose of this review is to draw up a statement on current knowledge available on damage control.
References were obtained from recent review articles, personal files, and Medline database research of English and French publications. All categories of articles on this topic have been selected.
Historical damage control surgery, that consist of abbreviated laparotomy with second-look after resuscitation, is now included in a wider concept called "damage control resuscitation", addressing the lethal triad (coagulopathy, hypothermia and acidosis) at an early phase. Care is focused on coagulopathy prevention. Early resuscitation, or damage control ground zero, has been improved: aggressive management of hypothermia, bleeding control techniques, permissive hypotension concept and early use of vasopressors. Transfusion practices also have evolved: early platelets and coagulation factors administration, use of hemostatic agents like recombinant FVIIa, whole blood transfusion, denote the damage control hematology. Progress in surgical practices and development of arteriographic techniques lead to wider indications of damage control strategy.
损伤控制是一种针对出血性创伤患者的治疗策略,包括与围手术期复苏相关的最小化抢救手术。本综述的目的是就损伤控制的现有知识起草一份声明。
参考文献来自近期的综述文章、个人档案以及对英文和法文出版物的Medline数据库检索。已选取了关于该主题的所有类别文章。
历史上的损伤控制手术,包括复苏后进行二次探查的简化剖腹术,现在已被纳入一个更广泛的概念,即“损伤控制复苏”,该概念在早期阶段应对致死三联征(凝血功能障碍、体温过低和酸中毒)。治疗重点在于预防凝血功能障碍。早期复苏,即损伤控制的起始点,已得到改进:积极处理体温过低、出血控制技术、允许性低血压概念以及早期使用血管升压药。输血实践也有了发展:早期输注血小板和凝血因子、使用重组凝血因子VIIa等止血剂、输注全血,这些都体现了损伤控制血液学。外科手术实践的进展和血管造影技术的发展导致损伤控制策略的适应证更广泛。