Department of Gynecology, Cancer Center, IRCCS Humanitas Clinical Institute, Via Manzoni 56, 20089 Rozzano, Milan, Italy.
Placenta. 2011 Sep;32 Suppl 3:S224-31. doi: 10.1016/j.placenta.2011.06.017. Epub 2011 Jul 18.
The implementation of early detection protocols and advanced treatment strategies has significantly improved survival outcomes for gynecologic cancer patients. The improvement of oncological outcomes has led to an increased attention toward Quality of Life issues, including the childbearing potential for young women. Traditionally the surgical treatment of cervical, endometrial and ovarian cancers involves the removal of the uterus and adnexa, irrespective of the impact on fertility and parenthood and regardless of patient desires. For young women affected by gynecological malignancies at an apparently early stage, fertility-sparing procedures could be offered. The aim of our review is to going through the available evidence in the Literature and to evaluate the current state of art regarding fertility-sparing procedures for women with gynecological malignancies in terms of oncological and fertility outcomes.
早期检测方案和先进治疗策略的实施显著改善了妇科癌症患者的生存结果。肿瘤学结果的改善使得人们越来越关注生活质量问题，包括年轻女性的生育潜力。传统上，宫颈癌、子宫内膜癌和卵巢癌的手术治疗包括子宫和附件的切除，而不考虑对生育能力和父母身份的影响，也不考虑患者的意愿。对于在明显早期阶段受到妇科恶性肿瘤影响的年轻女性，可以提供保留生育能力的手术。我们的综述目的是查阅文献中的现有证据，并评估保留生育能力的手术在妇科恶性肿瘤女性中的肿瘤学和生育结局方面的最新技术水平。
