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妇科恶性肿瘤患者的肿瘤生育学与生育力保存:我们今天处于什么位置?

Oncofertility and Fertility Preservation for Women with Gynecological Malignancies: Where Do We Stand Today?

机构信息

Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Huddinge, 14186 Stockholm, Sweden.

Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Huddinge, 14186 Stockholm, Sweden.

出版信息

Biomolecules. 2024 Aug 3;14(8):943. doi: 10.3390/biom14080943.

Abstract

Oncofertility is a growing medical and research field that includes two main areas: oncology and reproductive medicine. Nowadays, the percentage of patients surviving cancer has exponentially increased, leading to the need for intervention for fertility preservation in both men and women. Specifically, gynecological malignancies in women pose an additional layer of complexity due to the reproductive organs being affected. In the present review, we report fertility preservation options with a cancer- and stage-specific focus. We explore the drawbacks and the necessity for planning fertility preservation applications during emergency statuses (i.e., the COVID-19 pandemic) and comment on the importance of repro-counseling for multifaceted patients during their oncological and reproductive journey.

摘要

肿瘤生育力保护是一个日益发展的医学和研究领域,包括两个主要领域:肿瘤学和生殖医学。如今,癌症患者的存活率呈指数级增长,这导致男性和女性都需要进行生育力保护干预。具体来说,女性的妇科恶性肿瘤由于生殖器官受到影响,增加了一层复杂性。在本综述中,我们报告了以癌症和分期为重点的生育力保护选择。我们探讨了在紧急情况下(如 COVID-19 大流行)进行生育力保护应用的缺点和必要性,并评论了在肿瘤学和生殖旅程中对多方面患者进行生殖咨询的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8e4/11353009/37096172e8a5/biomolecules-14-00943-g001.jpg

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