• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

奥克斯纳医院对儿童急性淋巴细胞白血病的治疗经验。

The ochsner experience with acute lymphoblastic leukemia in childhood.

作者信息

Schorin M A, Ducos R S

机构信息

Section on Pediatric Hematology-Oncology, Ochsner Clinic and Alton Ochsner Medical Foundation, New Orleans, LA.

出版信息

Ochsner J. 2000 Oct;2(4):203-8.

PMID:21765697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3117505/
Abstract

Pediatricians at Ochsner Clinic and Alton Ochsner Medical Foundation have treated children with acute lymphoblastic leukemia for the past 17 years with excellent results. Although a single institution, and small in comparison to the national cooperative groups, we have achieved results comparable to the most successful national groups. In collaboration with the Dana-Farber Cancer Institute in Boston, MA, we have pursued several themes of study, including the comparison of various drugs, doses, and schedules of administration in the context of an investigational window in previously untreated patients. Schedules and dosages of radiation for prevention of relapse of leukemia in the central nervous system have also been studied with interesting results.

摘要

在过去17年里,奥施纳诊所和奥尔顿·奥施纳医学基金会的儿科医生一直致力于治疗急性淋巴细胞白血病患儿,并取得了优异的成果。尽管我们只是一家机构,且与全国性合作组织相比规模较小,但我们所取得的成果可与最成功的全国性组织相媲美。我们与马萨诸塞州波士顿的达纳-法伯癌症研究所合作,开展了多个研究主题,包括在未经治疗的患者的研究窗口期内,比较各种药物、剂量和给药方案。我们还研究了预防中枢神经系统白血病复发的放疗方案和剂量,结果令人感兴趣。

相似文献

1
The ochsner experience with acute lymphoblastic leukemia in childhood.奥克斯纳医院对儿童急性淋巴细胞白血病的治疗经验。
Ochsner J. 2000 Oct;2(4):203-8.
2
Childhood T-cell acute lymphoblastic leukemia: the Dana-Farber Cancer Institute acute lymphoblastic leukemia consortium experience.儿童T细胞急性淋巴细胞白血病:达纳-法伯癌症研究所急性淋巴细胞白血病联盟的经验
J Clin Oncol. 2003 Oct 1;21(19):3616-22. doi: 10.1200/JCO.2003.10.116.
3
Excellent therapeutic efficacy and minimal late neurotoxicity in children treated with 18 grays of cranial radiation therapy for high-risk acute lymphoblastic leukemia: a 7-year follow-up study of the Dana-Farber Cancer Institute Consortium Protocol 87-01.对高危急性淋巴细胞白血病患儿采用18格雷颅部放射治疗的卓越治疗效果及最小的晚期神经毒性:达纳-法伯癌症研究所联盟方案87-01的7年随访研究
Cancer. 2001 Jul 1;92(1):15-22. doi: 10.1002/1097-0142(20010701)92:1<15::aid-cncr1286>3.0.co;2-w.
4
Favorable outcome for adolescents with acute lymphoblastic leukemia treated on Dana-Farber Cancer Institute Acute Lymphoblastic Leukemia Consortium Protocols.在达纳-法伯癌症研究所急性淋巴细胞白血病协作组方案下接受治疗的青少年急性淋巴细胞白血病患者的良好预后。
J Clin Oncol. 2007 Mar 1;25(7):813-9. doi: 10.1200/JCO.2006.08.6397.
5
Brain tumors after cranial irradiation for childhood acute lymphoblastic leukemia. A 13-year experience from the Dana-Farber Cancer Institute and the Children's Hospital.
Cancer. 1987 Apr 15;59(8):1506-8. doi: 10.1002/1097-0142(19870415)59:8<1506::aid-cncr2820590819>3.0.co;2-p.
6
Management of Ontario children with acute lymphoblastic leukemia by the Dana-Farber Cancer Institute protocols.采用达纳-法伯癌症研究所方案对安大略省急性淋巴细胞白血病患儿进行管理。
CMAJ. 1989 Oct 1;141(7):693-7.
7
Comparative results of two intensive treatment programs for childhood acute lymphoblastic leukemia: The Berlin-Frankfurt-Münster and Dana-Farber Cancer Institute protocols.儿童急性淋巴细胞白血病两种强化治疗方案的比较结果:柏林-法兰克福-明斯特方案与达纳-法伯癌症研究所方案
Ann Oncol. 1991 Nov-Dec;2(10):745-9. doi: 10.1093/oxfordjournals.annonc.a057856.
8
Neuropsychological outcomes from a randomized trial of triple intrathecal chemotherapy compared with 18 Gy cranial radiation as CNS treatment in acute lymphoblastic leukemia: findings from Dana-Farber Cancer Institute ALL Consortium Protocol 95-01.与18 Gy颅脑放疗相比,三联鞘内化疗作为急性淋巴细胞白血病中枢神经系统治疗的随机试验的神经心理学结果:来自达纳-法伯癌症研究所急性淋巴细胞白血病联盟方案95-01的研究结果
J Clin Oncol. 2007 Nov 1;25(31):4914-21. doi: 10.1200/JCO.2007.10.8464.
9
Treatment of childhood acute lymphoblastic leukemia: results of Dana-Farber Cancer Institute/Children's Hospital Acute Lymphoblastic Leukemia Consortium Protocol 85-01.儿童急性淋巴细胞白血病的治疗:达纳-法伯癌症研究所/儿童医院急性淋巴细胞白血病协作组85-01方案的结果
J Clin Oncol. 1994 Apr;12(4):740-7. doi: 10.1200/JCO.1994.12.4.740.
10
The Dana Farber Consortium Protocol for the Treatment of Adolescents and Young Adults With Acute Lymphoblastic Leukemia: A Single Institution Experience in Saudi Arabia.达纳-法伯青少年和青年急性淋巴细胞白血病治疗联盟方案:沙特阿拉伯一家机构的经验
Clin Lymphoma Myeloma Leuk. 2017 May;17(5):320-325. doi: 10.1016/j.clml.2017.02.008. Epub 2017 Feb 16.

引用本文的文献

1
Recent publications by ochsner authors.奥克斯纳作者近期发表的作品。
Ochsner J. 2001 Apr;3(2):117-9.

本文引用的文献

1
Cognitive sequelae in children treated for acute lymphoblastic leukemia with dexamethasone or prednisone.接受地塞米松或泼尼松治疗的急性淋巴细胞白血病患儿的认知后遗症。
J Pediatr Hematol Oncol. 2000 May-Jun;22(3):206-13. doi: 10.1097/00043426-200005000-00004.
2
The three asparaginases. Comparative pharmacology and optimal use in childhood leukemia.三种天冬酰胺酶。儿童白血病中的比较药理学及最佳应用。
Adv Exp Med Biol. 1999;457:621-9.
3
Prognostic significance of early response to a single dose of asparaginase in childhood acute lymphoblastic leukemia.单剂量天冬酰胺酶早期反应在儿童急性淋巴细胞白血病中的预后意义
J Pediatr Hematol Oncol. 1999 Jan-Feb;21(1):6-12. doi: 10.1097/00043426-199901000-00003.
4
Acute neurotoxicity in children with B-precursor acute lymphoid leukemia: an association with intermediate-dose intravenous methotrexate and intrathecal triple therapy--a Pediatric Oncology Group study.B 前体急性淋巴细胞白血病患儿的急性神经毒性:与中剂量静脉注射甲氨蝶呤和鞘内三联疗法的关联——一项儿科肿瘤学组研究
J Clin Oncol. 1998 May;16(5):1712-22. doi: 10.1200/JCO.1998.16.5.1712.
5
Toxicity of CNS prophylaxis for childhood leukemia.儿童白血病中枢神经系统预防的毒性
Oncology (Williston Park). 1997 Feb;11(2):259-64; discussion 264-5.
6
Risk factors for intellectual and educational sequelae of cranial irradiation in childhood acute lymphoblastic leukaemia.儿童急性淋巴细胞白血病头颅照射导致智力和教育后遗症的危险因素。
Br J Cancer. 1996 Mar;73(6):825-30. doi: 10.1038/bjc.1996.145.
7
Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia.对急性淋巴细胞白血病患儿进行风险分类和治疗分配的统一方法。
J Clin Oncol. 1996 Jan;14(1):18-24. doi: 10.1200/JCO.1996.14.1.18.
8
Comparative pharmacokinetic studies of three asparaginase preparations.三种天冬酰胺酶制剂的比较药代动力学研究。
J Clin Oncol. 1993 Sep;11(9):1780-6. doi: 10.1200/JCO.1993.11.9.1780.
9
Treatment of childhood acute lymphoblastic leukemia: results of Dana-Farber Cancer Institute/Children's Hospital Acute Lymphoblastic Leukemia Consortium Protocol 85-01.儿童急性淋巴细胞白血病的治疗:达纳-法伯癌症研究所/儿童医院急性淋巴细胞白血病协作组85-01方案的结果
J Clin Oncol. 1994 Apr;12(4):740-7. doi: 10.1200/JCO.1994.12.4.740.
10
Intellectual performance after presymptomatic cranial radiotherapy for leukaemia: effects of age and sex.白血病症状前颅脑放疗后的智力表现:年龄和性别的影响。
Arch Dis Child. 1995 Aug;73(2):136-40. doi: 10.1136/adc.73.2.136.