Paulson Daniel, Bowen Mary Elizabeth, Lichtenberg Peter A
Department of Psychology and Institute of Gerontology, Wayne State University, Detroit, MI 48202-3801, USA.
J Aging Res. 2011;2011:912680. doi: 10.4061/2011/912680. Epub 2011 Jul 9.
Based in successful aging theory and terminal cognitive drop research, this paper investigates cerebrovascular burden (CVB), depressive symptoms, and cognitive decline as threats to longevity. A subsample of stroke-free women over the age of 80 was identified in the Health and Retirement Survey (years 2000-2008). Mortality at 2, 6, and 8 year intervals was predicted using CVB (diabetes, heart disease, hypertension), depressive symptoms (Center for Epidemiological Studies Depression Scale), and cognitive decline (decline of 1 standard deviation or more on the 35-point Telephone Interview for Cognitive Status over 2 years). At most waves (2002, 2004, and 2006) mortality was predicted by CVB, depressive symptoms, and cognitive drop measured 2 years prior. CVB and depressive symptoms at the 2000 wave predicted mortality at 6 and 8 years. Older women with the greatest longevity had low CVB, robust cognitive functioning, and few depression symptoms, supporting successful aging theory and terminal cognitive drop.
基于成功老龄化理论和晚期认知衰退研究，本文将脑血管负担（CVB）、抑郁症状和认知衰退作为长寿的威胁进行调查。在健康与退休调查（2000 - 2008年）中确定了一个80岁以上无中风女性的子样本。使用脑血管负担（糖尿病、心脏病、高血压）、抑郁症状（流行病学研究中心抑郁量表）和认知衰退（在两年内35分认知状态电话访谈中下降1个标准差或更多）来预测2年、6年和8年间隔的死亡率。在大多数调查周期（2002年、2004年和2006年），死亡率由两年前测量的脑血管负担、抑郁症状和认知衰退来预测。2000年周期的脑血管负担和抑郁症状预测了6年和8年的死亡率。寿命最长的老年女性脑血管负担低、认知功能强健且抑郁症状少，这支持了成功老龄化理论和晚期认知衰退。
