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妊娠急性脂肪肝

Acute fatty liver of pregnancy.

作者信息

Collado Ferrer María, Collado Ferrer Linda, Serrano Alfonso

机构信息

Department of Medicine, HIMA-San Pablo Caguas Hospital, Caguas, Puerto Rico.

出版信息

Bol Asoc Med P R. 2010 Oct-Dec;102(4):51-3.

Abstract

A 17-year-old-female at 39 weeks gestation, presented with pelvic pain, proteinuria and a decrease in fetal heart rate. Timely caesarean section was performed. The postoperative course was complicated by acute renal failure, acute pancreatitis, acute liver failure, anemia, thrombocytopenia, systemic inflammatory response syndrome (SIRS), prolonged coagulopathy, hyperbilirubinemia, ecclampsia, and psychosis. The clinical features and laboratory abnormalities, in conjunction with the timing of gestational age, led to the diagnosis of acute fatty liver of pregnancy. Prompt diagnosis and supportive care in an intensive care unit provided for a positive outcome.

摘要

一名孕39周的17岁女性,出现盆腔疼痛、蛋白尿及胎儿心率下降。及时进行了剖宫产。术后出现急性肾衰竭、急性胰腺炎、急性肝衰竭、贫血、血小板减少、全身炎症反应综合征(SIRS)、凝血功能障碍延长、高胆红素血症、子痫和精神病等并发症。临床特征和实验室异常,结合孕周,诊断为妊娠急性脂肪肝。在重症监护病房及时诊断并给予支持治疗,取得了良好的效果。

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