[新型紧凑型凝血酶原时间-国际标准化比值测量装置在儿科治疗中的评估]
[Evaluation of a new compact prothrombin time-international normalized ratio measurement device in pediatric management].
作者信息
Maekawa Y, Sakawa T, Umezu K, Ohashi N, Harada Y, Yasukochi S, Takigiku K, Matsui H, Inoue N, Morimoto Y, Watanabe S, Mori H
机构信息
Division of Cardiovascular Surgery, Nagano Children's Hospital, Azumino, Japan.
出版信息
Kyobu Geka. 2011 Jul;64(7):537-9.
BACKGROUND
In a pediatric setting, the need for lifetime oral anticoagulation is increasing because of currency of extracardiac total cavo-pulmonary connection (TCPC) and pediatric valve surgery. We evaluated a new compact device "CoaguChek XS" for measuring prothrombin time-internatinal normalized ratio (PT-INR).
METHODS
The international normalized ratio (INR) values obtained from 71 patients (223 samples) by a CoaguChek XS were compared with those obtained by a laboratory-based coagulation analyzer.
RESULTS
The values from the CoaguChek XS had a significant correlation with the laboratory based results. (r2 = 0.92, p < 0.01, regression line y = 1.05 x -0.02).
CONCLUSION
The CoaguChek XS will be useful in pediatric management.
背景
在儿科领域，由于心外全腔静脉-肺动脉连接术（TCPC）和小儿瓣膜手术的普及，终身口服抗凝治疗的需求正在增加。我们评估了一种用于测量凝血酶原时间-国际标准化比值（PT-INR）的新型紧凑型设备“CoaguChek XS”。
方法
将通过CoaguChek XS从71例患者（223个样本）获得的国际标准化比值（INR）值与通过基于实验室的凝血分析仪获得的值进行比较。
结果
CoaguChek XS获得的值与基于实验室的结果具有显著相关性。（r2 = 0.92，p < 0.01，回归线y = 1.05x - 0.02）。
结论
CoaguChek XS在儿科管理中将很有用。
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