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接受间歇性腹膜透析治疗的终末期肾衰竭患者腹膜中性粒细胞中的过氧化物酶活性

Peroxidase activity in peritoneal neutrophils of patients with terminal renal failure treated by intermittent peritoneal dialysis.

作者信息

Sułowicz W, Hanicki Z, Labza H, Basta A

机构信息

Department of Nephrology, Medical Academy Kraków, Poland.

出版信息

Med Interne. 1990 Apr-Jun;28(2):135-8.

PMID:2176739
Abstract

Peroxidase activity was assessed cytochemically in the peritoneal dialysate neutrophils of 50 patients with terminal renal failure treated by intermittent peritoneal dialysis. In 22 patients cells were harvested for the second time after they developed peritonitis as a complication of the treatment. The results obtained were compared with those in the control group consisting of 30 patients with normal renal function. The patients treated by peritoneal dialysis showed both in the complication-free period and in the course of peritonitis significantly higher peroxidase activity in the neutrophils, as revealed by the semiquantitative score test. In the course of peritonitis, the neutrophils peroxidase activity was significantly lower than in the complication-free period.

摘要

采用细胞化学方法对50例终末期肾衰竭患者进行间歇性腹膜透析治疗时腹膜透析液中的中性粒细胞过氧化物酶活性进行了评估。其中22例患者在发生腹膜炎(治疗并发症)后第二次采集细胞。将所得结果与由30例肾功能正常的患者组成的对照组进行比较。通过半定量评分试验发现,接受腹膜透析治疗的患者在无并发症期和腹膜炎病程中,中性粒细胞中的过氧化物酶活性均显著更高。在腹膜炎病程中,中性粒细胞过氧化物酶活性显著低于无并发症期。

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