Sułowicz W, Lisiewicz J, Kosiniak-Kamysz A
Department of Nephrology, Medical Academy, J. Dietl's Hospital, Kraków, Poland.
Rom J Intern Med. 1991 Jul-Dec;29(3-4):167-72.
Acid phosphatase (AcP), beta-glucuronidase (GR) and N-acetyl-beta-D-glucosaminidase (NAG) activity was determined, using semiquantitative cytochemical methods, in the peritoneal fluid lymphocytes obtained from 50 patients with terminal renal failure treated by intermittent peritoneal dialysis. The control group included 30 subjects with normal renal function. The percentage of AcP and NAG-positive lymphocytes was significantly lower and that of the GR-positive cells significantly higher in dialysed patients than in the control group. A group of 22 dialysed patients with bacterial peritonitis showed a significant increase of the percentage of NAG-positive lymphocytes as compared with both the subjects in the control group and the peritonitis-free dialysed ones. Changes of the lymphocytes enzymatic activities were distinct in cells exhibiting the granular reaction type, and to a much lesser extent in those showing granular diffuse reaction.
采用半定量细胞化学方法，测定了50例接受间歇性腹膜透析治疗的终末期肾衰竭患者腹膜液淋巴细胞中的酸性磷酸酶（AcP）、β-葡萄糖醛酸酶（GR）和N-乙酰-β-D-氨基葡萄糖苷酶（NAG）活性。对照组包括30例肾功能正常的受试者。与对照组相比，透析患者中AcP和NAG阳性淋巴细胞的百分比显著降低，而GR阳性细胞的百分比显著升高。与对照组受试者和无腹膜炎的透析患者相比，一组22例患有细菌性腹膜炎的透析患者中NAG阳性淋巴细胞的百分比显著增加。淋巴细胞酶活性的变化在表现为颗粒反应类型的细胞中明显，而在表现为颗粒弥漫反应的细胞中变化程度要小得多。
